J. L. Rasgon

Multiple bouts of blood feeding in mosquitoes allow prolonged survival and are predicted to increase viral transmission during drought

This study shows that repeated blood feeding during drought increases mosquito survival and viral transmission potential by enhancing activity and CO2 sensing.

In Silico Characterization of Intracellular Localization Signals and Structural Features of Mosquito Densovirus (MDV) Viral Proteins

This study identifies putative nuclear localization and export signals in mosquito densovirus proteins using in silico analysis, enhancing understanding of viral protein trafficking and potential applications in mosquito control.

NS2B-D55E and NS2B-E65D Variations are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model

This study identifies NS2B-55 and NS2B-65 variations as responsible for differences in NS2B-NS3 protease activity between JEV genotype I and III using fluorogenic peptide assays.

Wolbachia-induced inhibition of O'nyong nyong virus in Anopheles mosquitoes is mediated by Toll signaling and modulated by cholesterol

This study shows Wolbachia inhibits Onyong nyong virus in Anopheles mosquitoes via Toll signaling, but cholesterol suppresses this effect by modulating Toll signaling.

Eilat virus (EILV) causes superinfection exclusion against West NILE virus (WNV) in a strain specific manner in Culex tarsalis mosquitoes

This study shows Eilat virus (EILV) causes superinfection exclusion (SIE) against two WNV strains in C6/36 cells but has strain-specific effects in Culex tarsalis mosquitoes.

Temperature affects viral kinetics and vectorial capacity of Aedes aegypti mosquitoes co-infected with Mayaro and Dengue viruses

This study investigates how temperature affects the infection dynamics and transmission potential of Mayaro and Dengue viruses in Aedes aegypti mosquitoes, both singly and in co-infections.

Dehydration stress and Mayaro virus vector competence in Aedes aegypti

This study examines how dehydration stress affects mortality and Mayaro virus vector competence in Aedes aegypti, finding no impact on viral transmission but significant effects on survival and blood feeding.

CRISPR/Cas9-mediated mutagenesis of the Asian Citrus Psyllid, Diaphorina citri

This paper develops CRISPR/Cas9 methods for genetic modification of Diaphorina citri to combat Huanglongbing disease spread.

Sindbis virus is suppressed in the yellow fever mosquito Aedes aegypti by ATG-6/Beclin-1 mediated activation of autophagy

This study shows that activating autophagy in Aedes aegypti mosquitoes reduces Sindbis virus production using a recombinant virus expressing an autophagy activator.

Variable effects of Wolbachia on alphavirus infection in Aedes aegypti

This paper examines how two Wolbachia strains affect alphavirus infections in Aedes aegypti mosquitoes, finding variable effects including enhancement and suppression of viral infections.

Signatures of adaptive decreased virulence of deformed wing virus in an isolated population of wild honey bees (Apis mellifera)

The paper investigates DWV virulence in honey bees, finding that isolates from an isolated population show reduced virulence, supporting adaptive evolution.

Culex tarsalis is a competent host of the insect-specific alphavirus Eilat virus (EILV)

This study identifies Culex tarsalis as a competent host for Eilat virus and explores its transmission routes and tissue tropism in mosquitoes and other potential hosts.

Anopheles albimanus is a potential alphavirus vector in the Americas

This study shows Anopheles albimanus can efficiently transmit certain alphaviruses but not flaviviruses, highlighting its potential as a vector for emerging pathogens.

Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes

This study shows that the mosquito gene Man2 affects arbovirus infection and Wolbachia interactions differently depending on the pathogen and Wolbachia strain.

Sexual transmission of Anopheles gambiae densovirus (AgDNV) leads to disseminated infection in mated females

This study shows that Anopheles gambiae densovirus (AgDNV) is transmitted from infected males to females during mating, leading to disseminated infection in females but not vertical transmission to offspring.

In vitro and in vivo co-infection and super-infection dynamics of Mayaro and Zika viruses in mosquito and vertebrate backgrounds

This study examines co-infection and super-infection dynamics of Mayaro and Zika viruses in mosquito and vertebrate cells, finding negative impacts on Zika replication and transmission.

Everything you wanted to know about Mayaro virus but were afraid to ask: Characterization and lifecycle of Mayaro virus in vertebrate and invertebrate cellular backgrounds

This study characterizes the replication, entry mechanisms, and pathogenesis of Mayaro virus in vertebrate and invertebrate cells, identifying pH-dependent endocytosis and macropinocytosis as entry routes and cytopathic effects associated with apoptosis.

Mayaro Virus Infection Elicits an Innate Immune Response in Anopheles stephensi

This study examines the transcriptomic and small RNA responses of Anopheles stephensi to Mayaro virus infection, identifying regulated genes, novel miRNAs, and an siRNA response targeting the virus.

Vectorchip: Microfluidic platform for highly parallel bite by bite profiling of mosquito-borne pathogen transmission

Vectorchip enables high-throughput analysis of individual mosquito bites to study pathogen transmission dynamics and infectious viral particles.