Author

K. Plath

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

J. Langerman· 3 shared A. Purkayastha· 2 shared B. Konda· 2 shared B. N. Gomperts· 2 shared B. R. Stripp· 2 shared D. W. Shia· 2 shared P. Vijayaraj· 2 shared T. M. Rickabaugh· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

J. Langerman

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Optimization of RNA Pepper sensors for the detection of arbitrary RNA targets

A. Tang, A. Afasizheva, C. Cano, K. Plath, D. L. Black, E. Franco

This paper develops and optimizes Pepper RNA sensors for detecting arbitrary RNA targets with high brightness and sensitivity.

bioRxiv · Jun 1, 2023Biochemistry

Secretion encoded single-cell sequencing (SEC-seq) uncovers gene expression signatures associated with high VEGF-A secretion in mesenchymal stromal cells

S. Udani, J. Langerman, D. Koo, S. Baghdasarian, B. Cheng, S. Kang, C. Soemardy, J. de Rutte, K. Plath, D. Di Carlo

SEC-seq links cell secretions to transcriptomes, revealing VEGF-A secretion heterogeneity and a unique gene signature in MSCs with high secretion.

bioRxiv · Jan 7, 2023Bioengineering

A molecular atlas of proximal airway identifies subsets of known airway cell types revealing details of the unique molecular pathogenesis of Cystic Fibrosis

G. Carraro, J. Langerman, S. Sabri, Z. Lorenzana, A. Purkayastha, B. Konda, C. J. Aros, B. A. Calvert, A. Szymaniak, E. Wilson, M. Mulligan, P. Bhatt, P. Vijayaraj, C. Yao, D. W. Shia, , B. N. Gomperts

The paper uses single-cell transcriptomics to analyze proximal airway epithelium in CF and healthy donors, identifying molecular changes linked to CF pathogenesis.

Nature Medicine · May 6, 2021Peer-reviewedCell Biology

Xist-seeded nucleation sites form local concentration gradients of silencing proteins to inactivate the X-chromosome

Y. Markaki, J. G. Chong, C. Luong, S. Y. X. Tan, Y. Wang, E. C. Jacobson, D. Maestrini, I. Dror, B. A. Mistry, J. Schoeneberg, A. Banerjee, M. Guttman, T. Chou, K. Plath

This study identifies Xist-seeded nucleation sites that create local concentration gradients of silencing proteins, leading to X-chromosome inactivation through macromolecular crowding.

bioRxiv · Nov 22, 2020Cell Biology

Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stemcell-derived airway repair response

A. Purkayastha, C. Sen, G. Garcia, J. Langerman, P. Vijayaraj, D. W. Shia, L. K. Meneses, T. M. Rickabaugh, A. Mulay, B. Konda, M. S. Sim, B. R. Stripp, K. Plath, V. Arumugaswami, B. N. Gomperts

This study shows that cigarette smoke exposure increases SARS-CoV-2 infection severity in airway cultures by reducing interferon response and ABSC proliferation.

bioRxiv · Jul 28, 2020Cell Biology