M. Jeon

Functional regulation of 4D metabolic network between multienzyme glucosome condensates and mitochondria

The paper investigates how glucosomes and mitochondria form a 4D metabolic network to regulate glucose metabolism in human cells.

Functional oscillation of a multienzyme glucosome assembly during cell cycle progression

The paper discovers that glucosomes oscillate during the cell cycle in human cells, linking their size-dependent spatiotemporal dynamics to glucose metabolism's role in cell cycle progression.

Vernalization-triggered expression of the antisense transcript COOLAIR is mediated by CBF genes

This study shows that CBF genes regulate COOLAIR expression during vernalization in Arabidopsis, but COOLAIR is not essential for the vernalization response.

Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge

The paper reports on a DREAM Challenge to predict multi-target kinase inhibitors for RET-based tumors and Tauopathy, using neural network-based machine learning approaches.

Crowdsourced mapping of unexplored target space of kinase inhibitors

The paper benchmarks predictive models for kinase inhibitor potencies using crowdsourced data and identifies new compound-kinase interactions.

A new family of neural wiring receptors across bilaterians defined by phylogenetic, biochemical and structural evidence

The paper identifies Dprs and DIPs as part of an ancient bilaterian receptor family involved in neural wiring, supported by phylogenetic, biochemical, and structural evidence.