Author

M. O. Schmidt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Wellstein· 2 shared E. Chen· 2 shared A. C. Foulger· 1 shared A. D. Mays· 1 shared A. J. Kiliti· 1 shared A. K. Gonsiewski· 1 shared A. L. Coleman-Hulbert· 1 shared A. Nasir· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

A. Wellstein

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Author profile →

4 papers

Recent·Most cited

Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment

D. Ganguly, M. O. Schmidt, M. Coleman, T.-V. Ngo, N. Sorrelle, A. T. Dominguez, J. Toombs, C. Lewis, Y. Fang, F. V. Mora, D. Gallego-Ortega, A. Wellstein, R. A. Brekken

This study identifies pleiotrophin as a driver of a pro-metastatic immune niche in breast cancer, showing its role in immune suppression and metastasis, and highlights its potential as a therapeutic target.

bioRxiv · May 2, 2022Cancer Biology

Cell-free, methylated DNA in blood samples reveals tissue-specific, cellular damage from radiation treatment

M. E. Barefoot, N. Loyfer, A. J. Kiliti, M. O. Schmidt, S. Shabi-Porat, S. Jain, S. M. Roth, A. P. McDeed, N. Shahrour, E. Ballew, Y.-T. Lin, H.-H. Li, A. D. Mays, S. Rudra, A. T. Riegel, , A. Wellstein

This study uses cell-free methylated DNA in blood to detect tissue-specific damage from radiation treatment in mice and cancer patients.

bioRxiv · Apr 12, 2022Cancer Biology

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

S. A. Banse, C. A. Sedore, E. Johnson, A. L. Coleman-Hulbert, B. Onken, D. Hall, E. G. Jackson, P. Huynh, A. C. Foulger, S. Guo, T. Garrett, J. Xue, D. Inman, M. L. Morshead, W. T. Plummer, , P. C. Phillips

This study evaluates the lifespan and health effects of five compounds in Caenorhabditis nematodes, finding species- and strain-specific responses, assay-dependent outcomes, and uncoupling of lifespan and health effects.

bioRxiv · Nov 9, 2021Physiology

Environmentally Induced Sperm RNAs Transmit Cancer Susceptibility to Offspring in a Mouse Model

R. S. da Cruz, O. Dominguez, E. Chen, A. K. Gonsiewski, A. Nasir, M. I. Cruz, X. Zou, S. Galli, K. Makambi, M. McCoy, M. O. Schmidt, L. Jin, I. Peran, S. de Assis

This study shows that DDT exposure in male mice alters sperm RNAs, which transmit cancer susceptibility to female offspring through miRNA-10b, leading to increased tumor aggressiveness.

bioRxiv · Mar 23, 2020 · PreprintCancer Biology