P. L. Felgner

Defining the EM-signature of successful cell-transfection

The paper uses electron microscopy to identify unique structural changes in cells after transfection with Lipofectamine 2000 and 3000, providing a method to distinguish successfully transfected cells.

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

Novel functional insights from the Plasmodium falciparum sporozoite-specific proteome by probabilistic integration of 26 studies

This paper identifies sporozoite-specific and enriched proteins in Plasmodium falciparum by integrating 26 transcriptomic and proteomic studies, revealing key pathways and potential vaccine targets.

Distinct SARS-CoV-2 antibody reactivity patterns elicited by natural infection and mRNA Vaccination

The paper compares antibody reactivity patterns between natural SARS-CoV-2 infection and mRNA vaccination, finding that vaccination induces stronger and broader antibody responses, including cross-reactivity against SARS antigens.

Plasmodium falciparum serology: A comparison of two protein production methods for analysis of antibody responses by protein microarray

This study compares antibody responses to proteins produced by IVTT and purified recombinant systems on a protein microarray, finding greater responses to purified recombinants and variable correlation between expression systems.

Contribution of noncanonical antigens to virulence and adaptive immunity in human infection with enterotoxigenic E. coli

The paper identifies noncanonical antigens, EtpA and EatA, associated with ETEC virulence and immune response, suggesting their potential inclusion in vaccine design.

Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score

This paper identifies an antibody epitope and a risk score to predict severe COVID-19 outcomes with high specificity.

Distinct SARS-CoV-2 Antibody Reactivity Patterns in Coronavirus Convalescent Plasma Revealed by a Coronavirus Antigen Microarray

This study uses a coronavirus antigen microarray to identify distinct antibody reactivity patterns in SARS-CoV-2 convalescent plasma, showing high concordance with existing assays and revealing clusters with potential implications for treatment efficacy.

A Modular Microarray Imaging System for Highly Specific COVID-19 Antibody Testing

The paper introduces a low-cost, portable imaging system for specific COVID-19 antibody testing using microarrays, achieving performance comparable to expensive commercial readers.

Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Blood using a Coronavirus Antigen Microarray

This paper validates a coronavirus antigen microarray to distinguish SARS-CoV-2 convalescent blood from pre-pandemic controls, showing improved discrimination with spike and nucleoprotein antigens.

Analysis of Serologic Cross-Reactivity Between Common Human Coronaviruses and SARS-CoV-2 Using Coronavirus Antigen Microarray

The paper develops a coronavirus antigen microarray to study serologic cross-reactivity between common human coronaviruses and SARS-CoV-2, finding high IgG reactivity to common coronaviruses and low reactivity to SARS-CoV-2 with some cross-reactivity to conserved antigens.