Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
S. Sun, H. Gu, L. Cao, Q. Chen, Q. Ye, G. Yang, R.-T. Li, H. Fan, Y.-Q. Deng, X. Song, Y. Qi, M. Li, J. Lan, R. Feng, G. Yan, , C. Qin
A mouse-adapted SARS-CoV-2 strain with RBD mutations caused 100% mortality in aged male BALB/c mice and showed altered receptor binding affinity.
bioRxiv · Nov 10, 2020Microbiology