Author

S. Armstrong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 5 Microbiology· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 9 Research Focus:cancer & tumor microenvironment· 5 Organism:human· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

A. Kentsis· 3 shared E. Still· 3 shared R. Koche· 3 shared A. Krivtsov· 2 shared C. Reed· 2 shared E. de Stanchina· 2 shared F. Brown· 2 shared A. Augustine· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. Kentsis

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Sex Hormones Alter Pseudomonas aeruginosa Iron Acquisition and Virulence Factors

H. Ebrahim, N. Bryan, A. Collette, S. Armstrong, C. Bronowski, R. Floyd, J. Fothergill

This study investigates how sex hormones affect Pseudomonas aeruginosa iron acquisition and virulence in different media, finding hormone-specific changes in protein abundance and virulence pathways.

bioRxiv · Mar 12, 2024 · PreprintMicrobiology

The RAD51 paralogue HvXRCC2 regulates meiosis and recombination in barley

I. Colas, M. Macaulay, M. Arrieta, M. Schreiber, A. Sandhu, A. Augustine, M. Targonska-Karasek, S. Armstrong, R. Waugh, L. Ramsay

This study identifies HvXRCC2 as critical for meiosis and recombination in barley, showing reduced crossovers and infertility, contrasting with Arabidopsis.

bioRxiv · Oct 5, 2023 · PreprintPlant Biology

SARS-CoV-2 NSP12 associates with the TRiC complex and the P323L substitution is a host adaption.

M. Alruwaili, S. Armstrong, T. Prince, M. Erdmann, A. D. Davidson, D. A. Matthews, W. AlJabr, J. A. Hiscox

The paper identifies NSP12's interaction with the TRiC complex and shows the P323L substitution enhances viral adaptation by reducing sensitivity to PP2A perturbations.

bioRxiv · Mar 18, 2023 · PreprintMicrobiology

The mechanical arthropod vector Stomoxys calcitrans influences the outcome of lumpy skin disease virus infection in cattle

C. G. Cook, H. Munyanduki, P. C. Fay, N. Wijesiriwardana, K. Moffat, S. Gubbins, S. Armstrong, C. Batten, I. Dietrich, D. R. Greaves, K. Darpel, P. M. Beard

This study investigates how the mechanical transmission of lumpy skin disease virus (LSDV) by the stable fly Stomoxys calcitrans affects disease progression in cattle, finding that saliva and bite trauma accelerate disease kinetics.

bioRxiv · Mar 13, 2023 · PreprintMicrobiology

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

Y. M. Soto-Feliciano, C. Zhu, J. P. Morris, C.-h. Huang, R. P. Koche, Y.-j. Ho, A. Banito, C.-w. Chen, A. Shroff, S. Tian, L. Geulah, C.-c. Chen, M. Fennell, S. Armstrong, C. D. Allis, , S. W. Lowe

This study shows that MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer by affecting chromatin modifications and gene expression.

bioRxiv · Jun 7, 2022Cancer Biology

A JAK/STAT-Mediated Inflammatory Signaling Cascade Drives Oncogenesis In AF10-Rearranged AML

B. Chen, A. Deshpande, K. O. Barbosa, M. Kleppe, X. Lei, N. Yeddula, A. Rosa Campos, R. Wechsler-Reya, A. Bagchi, S. Meshinchi, C. J. Eaves, I. Jeremias, T. Haferlach, D. Frank, Z. Ronai, , A. Deshpande

This study identifies JAK1 as a therapeutic target in AF10-rearranged AML by showing its role in JAK/STAT-mediated inflammatory signaling and oncogenesis.

bioRxiv · Aug 31, 2020Cancer Biology

Peptidomimetic blockade of MYB in acute myeloid leukemia

K. Ramaswamy, L. Forbes, G. Minuesa, T. Gindin, F. Brown, M. Kharas, A. Krivtsov, S. Armstrong, E. Still, E. de Stanchina, B. Knoechel, R. Koche, A. Kentsis

This study develops a peptidomimetic inhibitor, MYBMIM, that blocks MYB:CBP/P300 complex assembly in AML cells, leading to apoptosis and reduced tumor growth in mice.

bioRxiv · Nov 20, 2017Cancer Biology

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

A. Henssen, R. Koche, J. Zhuang, E. Jiang, C. Reed, A. Eisenberg, E. Still, I. MacArthur, E. Rodriguez-Fos, S. Gonzalez, M. Puiggros, A. Blackford, C. Mason, E. De Stanchina, M. Gonen, , A. Kentsis

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.

bioRxiv · Feb 23, 2017Cancer Biology

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia

F. Brown, E. Still, P. Cifani, S. Takao, C. Reed, S. Ficarro, R. Koche, P. Romanienko, W. Mark, C. O'Donnell, B. Spitzer, C. Stutzke, A. Krivtsov, G. Pouliot, J. Marto, , A. Kentsis

This study identifies MEF2C phosphorylation as a marker of chemotherapy resistance in AML and shows that inhibiting this phosphorylation can overcome resistance in MEF2C-activated cells.

bioRxiv · Feb 9, 2017Cancer Biology