Author

T. Maruyama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:mouse· 4 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. Okumura· 2 shared A. Arimoto· 1 shared A. Samadi· 1 shared A. Toyoda· 1 shared C. B. Damoci· 1 shared C. J. Okumura· 1 shared C. Sakuma· 1 shared C.-S. Lin· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCancer Biology

C. Okumura

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A high-sensitivity ELISA for detection of human FGF18 in culture supernatants from tumor cell lines

Y. Tsuchiya, S. Komazawa-Sakon, M. Tanaka, T. Kanakogi, K. Moriwaki, H. Akiba, H. Yagita, K. Okumura, K. Entzminger, C. Okumura, T. Maruyama, H. Nakano

This paper develops a high-sensitivity ELISA for detecting human FGF18 in tumor cell culture supernatants and validates its use in detecting murine FGF18 in mouse sera.

bioRxiv · Jun 16, 2023Cancer Biology

Rapid engineering of SARS-CoV-2 therapeutic antibodies to increase breadth of neutralization including XBB.1.5 and BQ.1.1

K. C. Entzminger, J. K. Fleming, P. D. Entzminger, L. Y. Espinosa, A. Samadi, Y. Hiramoto, C. Okumura, T. Maruyama

This study engineers broadly neutralizing antibodies against SARS-CoV-2 variants using phage display and STEM technology, resulting in mAbs effective against XBB.1.5 and BQ.1.1.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Smart utilization of betaine lipids in giant clam Tridacna crocea

R. Sakai, N. Goto-Inoue, H. Yamashita, N. Aimoto, Y. Kitai, T. Maruyama

This study identifies DGCC as a key lipid used by giant clams to thrive in nutrient-poor environments through symbiotic algae.

bioRxiv · Jan 16, 2023 · PreprintZoology

Targeted single-cell genomics reveals novel host adaptation strategies of the symbiotic bacteria Endozoicomonas in Acropora tenuis coral

K. Ide, Y. Nishikawa, T. Maruyama, Y. Tsukada, M. Kogawa, H. Takeda, R. Wagatsuma, R. Miyaoka, Y. Nakano, K. Kinjo, M. Ito, M. Hosokawa, K. Yura, S. Suda, H. Takeyama

This study uses single-cell genomics to analyze Endozoicomonas bacteria in Acropora tenuis corals, revealing host-adaptive genes that may enhance coral stress tolerance.

bioRxiv · Apr 22, 2022Microbiology

Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

Y. Wang, K. Shiladardi, T. Hsu, K. O. Odinammadu, T. Maruyama, W. Wu, C.-S. Lin, C. B. Damoci, E. D. Spear, J.-Y. Shin, W. Hsu, S. Michaelis, H. J. Worman

This study shows that mice with permanently farnesylated prelamin A live nearly normal lifespans but show aging-related defects, suggesting prelamin A accumulation contributes to aging phenotypes.

bioRxiv · Nov 11, 2021Cell Biology

Prospective isolation of mouse and human hematopoietic stem cells using Plexin domain containing 2

Y. Tanaka, Y. Kubota, I. Lieberam, J. L. Barlow, J. W. Bramley, C. Sakuma, T. Shibata, M. Nakagawa, Y. Kurosawa, T. Maruyama, C. J. Okumura, T. Akuta, D. G. Kent, T. M. Jessell, S. Goyama, , T. Kitamura

This study identifies PLXDC2 as a marker for isolating hematopoietic stem cells (HSCs) in both mouse and human, showing its utility in transplantation and xenograft models.

bioRxiv · Sep 27, 2021 · PreprintCell Biology

Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus

T. Maeda, S. Takahashi, T. Yoshida, S. Shimamura, Y. Takaki, Y. Nagai, A. Toyoda, Y. Suzuki, A. Arimoto, H. Ishii, N. Satoh, T. Nishiyama, M. Hasebe, T. Maruyama, J. Minagawa, , S. Shigenobu

This study sequenced the genome of a kleptoplastic sea slug and found no evidence of algal gene transfer to the nucleus, showing photosynthesis can occur without nuclear gene transfer.

bioRxiv · Jun 16, 2020 · PreprintEvolutionary Biology