W. Cai

This study identifies colibactin-645 as a genotoxic metabolite that induces DNA double-strand breaks via a copper-mediated oxidative mechanism, revealing its role in colorectal cancer progression.

This study identifies the biosynthetic gene cluster for triacsins in Streptomyces aureofaciens and discovers a new producer species.

The paper identifies 196 differentially expressed proteins in TGF-β1-treated lung fibroblasts and finds that VLDLR and SDC2 are upregulated in silica-exposed lungs, with knockdown reducing collagen production.

This study identifies a new non-heme iron(II)-dependent enzyme mechanism for isonitrile formation, expanding known biosynthetic pathways.

This study identifies posttranslational modifications of RioK1 that regulate its stability and oncogenic activity in colorectal and gastric cancers.

This study identifies a novel family of polyketides in Clostridium acetobutylicum that regulate butanol production and differentiation processes.

The paper identifies a conserved gene cluster in Actinobacteria that synthesizes isonitrile lipopeptides (INLPs) via a unique thio-template mechanism and links it to metal transport in Mycobacterium marinum.

This study tests eDNA detection for invasive crayfish in rice terraces, finding it more sensitive than trapping and suggesting repeated sampling for reliable monitoring.