W. He

This paper develops a method to directly synthesize EM-visible gold nanoparticles on genetically encoded tags for single-molecule visualization in cells, achieving high labeling efficiency in both prokaryotic and eukaryotic cells.

This study shows Bclaf1 is degraded by alphaherpesvirus US3 and is critical for type I interferon signaling and antiviral immunity.

This paper introduces Hessian-SMLM, a method to reduce pixel-dependent readout noise in sCMOS cameras for single-molecule localization microscopy, improving imaging time resolution.