C. Cheng

This study identifies novel and validated QTLs for fiber quality traits in Upland cotton using a paternal backcross population and RILs, with some QTLs explaining over 10% of phenotypic variation.

This study identifies small molecules that modulate alternative splicing by targeting RNA G-quadruplexes through a high-throughput screen.

This study identifies a two-dimensional rate-yield tradeoff in evolved E. coli strains using multi-scale modeling.

This study shows that Tpm3.5 stabilizes F-actin networks in mouse lens fiber cells, maintaining tissue biomechanical properties and mechanical resilience.

This study identifies lncRNAs associated with cancer prognosis by integrating RNA-seq and microarray data across 20 cancer types.

This study uses metagenomic sequencing to identify pathogens in culture-negative infective endocarditis cases, providing antimicrobial resistance profiles without culturing.

This study shows that targeting the HIV-1 fusion peptide with specific immunogens induces cross-clade neutralizing antibodies in animals.

This study identifies how virus infection alters the tumor microenvironment and genetic programming in six virus-associated cancers using genomic data.

This study examines how mechanical strain affects the structure of mouse eye lenses, finding reversible and irreversible changes in microstructure depending on strain magnitude.

This paper introduces M2-seq, a method to infer RNA structures through chemical mapping and mutations, achieving accurate helix detection with low false positives in vitro and in complex biological environments.

The paper shows that sex chromosomes in Aedes aegypti are genetically differentiated over a large region, not just a small sex-determining region, and demonstrates how this can be used for accurate sex assignment and population genomic studies.