Author

J. Gong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Microbiology· 3 Bioengineering· 2 Plant Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 13 Organism:human· 7 Research Focus:cell type annotation· 6 Organism:mouse· 5 Research Focus:differential expression· 4 Assay:imaging· 4 Assay:bulk RNA-seq· 3 Research Focus:cell-cell communication· 3

Frequent Co-Authors

L. Wang· 2 shared S. Hu· 2 shared X. Li· 2 shared X. Wang· 2 shared Y. Liang· 2 shared Y. Wang· 2 shared Y. Zhang· 2 shared Z. Feng· 2 shared

Activity by Year

2019-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

L. Wang

Mutual co-authors in cluster

Author profile →

15 papers

Recent·Most cited

Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia

C. Chen, Y. Qin, Y. Xu, X. Wang, W. Lei, X. Shen, L. Chen, L. Wang, J. Gong, Y. Wang, S. Hu, D. Liu

This study identifies aquaporins in endothelial cells that regulate microvascular diameter in hyperglycemia, suggesting they are potential targets for diabetes-related vascular therapy.

Cardiovascular Research · Apr 22, 2024Peer-reviewedCell Biology

Sorcin-STAT3-Serpin E1/CCL5 axis can be the trigger of pancreatic cancer-associated new-onset diabetes

J. Gong, X. Wei, Z. Feng, J. Lou, Y. Sun, S. Hu, J. Wu, Y. Wu

This study identifies a Sorcin-STAT3-Serpin E1/CCL5 signaling axis that drives pancreatic cancer-associated new-onset diabetes by impairing beta-cells and elevating serpin E1 levels in peripheral blood.

bioRxiv · Jul 20, 2023 · PreprintCancer Biology

CAM5, WRKY53, and TGA5 regulate defense gene expression mediated by the volatile organic compound ethyl vinyl ketone

J. Gong, Z. Guo, Z. Wang, L. Yao, C. Zhao, S. Lin, S. Ma, Y. Shen

This paper identifies ethyl vinyl ketone (evk) as a signaling molecule in Arabidopsis thaliana, showing it activates defense genes via CAM5, WRKY53, and TGA5 through Ca2+ and H2O2 signaling.

bioRxiv · Jan 24, 2023 · PreprintPlant Biology

Prediction of Electric Fields Induced by Transcranial Magnetic Stimulation in the Brain using a Deep Encoder-Decoder Convolutional Neural Network

M. Tashli, M. S. Alam, J. Gong, C. Lewis, C. L. Peterson, H. Eldardiry, J. Atulasimha, R. L. Hadimani

This paper develops a deep convolutional neural network to predict induced electric fields from TMS in real-time using MRI data, achieving high accuracy with peak signal-to-noise ratios of 32.83dB and 28.01dB.

bioRxiv · Oct 27, 2022 · PreprintBioengineering

Gliotransmission orchestrates neuronal type-specific axon regeneration

F. Wang, K. T. Ruppell, S. Zhou, Y. Qu, Y. Shang, J. Gong, Y. Li, Y. Xiang

This study shows gliotransmission via adenosine signaling determines axon regeneration in specific neuronal types, with implications for CNS repair.

bioRxiv · May 20, 2022 · PreprintNeuroscience

AMPK mediates early activation of the unfolded protein response through a positive feedback loop in palmitate-treated muscle cells

J. Gong, L. Wang, W. Tao, Z. Liu, W. Li, Y. Liu, X. Chen, P. Zhang

This study shows AMPK and UPR interact via a positive feedback loop in muscle cells exposed to palmitate, with AMPK agonists enhancing UPR gene expression.

bioRxiv · Oct 12, 2021Physiology

DAB2IP inhibits p53 ubiquitin-mediated degradation by competitively binding to GRP75 and suppresses tumor malignancy in colon cancer

J. Shen, S. Feng, J. Deng, Q. Huang, D. Zhao, W. Jia, X. Li, D. Tao, J. Gong, D. Xie, L. Liu

This study identifies DAB2IP as a tumor suppressor in colon cancer that inhibits p53 degradation by competing with GRP75 for binding, thereby enhancing p53 stability and suppressing tumor growth.

bioRxiv · Jun 28, 2021 · PreprintCancer Biology

Targeting glucose metabolism sensitizes pancreatic cancer to MEK inhibition

L. Yan, B. Tu, J. Yao, J. Gong, A. Carugo, C. Bristow, Q. Wang, C. Zhu, B. Dai, Y. Kang, L. Han, N. Feng, Y. Jin, J. Fleming, T. Heffernan, , H. Ying

This study shows that combining glucose metabolism inhibition with MEK inhibition enhances apoptosis in pancreatic cancer cells by inducing ER stress.

bioRxiv · Jan 9, 2021Cancer Biology

SARS-CoV-2 manipulates the SR-B1-mediated HDL uptake pathway for its entry

C. Wei, L. Wan, Q. Yan, X. Wang, J. Zhang, Y. Zhang, J. Sun, X. Yang, J. Gong, C. Fan, X. Yang, Y. Wang, X. Wang, J. Li, H. Yang, , H. Zhong

This study shows SARS-CoV-2 uses the SR-B1-mediated HDL uptake pathway alongside ACE2 for entry, and blocking this pathway inhibits infection.

bioRxiv · Aug 13, 2020Microbiology

Digital spatial profiling of coronary plaques from persons living with HIV reveals high levels of STING and CD163 in macrophage enriched regions

C. N. Wanjalla, L. Guo, D. T. Fuller, M. Mashayekhi, S. Bailin, C. L. Gabriel, T. Temu, J. Gong, Y. Liang, R. Virmani, A. V. Finn, S. A. Kalams, S. A. Mallal, J. Miner, J. A. Beckman, J. R. Koethe

The paper uses digital spatial profiling to analyze coronary plaques from HIV-positive and HIV-negative individuals, finding higher CD163 and STING expression in HIV-positive plaques.

bioRxiv · Jul 28, 2020 · PreprintImmunology

Biologically excretable AIE dots for visualizing through the marmosets intravitally: horizons in future clinical nanomedicine

Z. Feng, S. Bai, J. Qi, C. Sun, Y. Zhang, X. Yu, H. Ni, D. Wu, X. Fan, D. Xue, S. Liu, M. Chen, J. Gong, P. Wei, M. He, , J. Qian

This study designs excretable AIE dots for deep-tissue imaging in marmosets, demonstrating their biocompatibility and excretion capabilities.

bioRxiv · May 26, 2020Bioengineering

New intranuclear symbiotic bacteria from macronucleus of Paramecium putrinum -- Candidatus Gortzia yakutica

A. Y. Beliavskaia, S. Garushyants, M. Logacheva, J. Gong, S. Zou, M. Gelfand, M. Rautian

The paper describes a new species of Holospora-like bacteria, Candidatus Gortzia yakutica, found in the macronucleus of Paramecium putrinum.

Diversity · May 15, 2020Peer-reviewedMicrobiology

Orthogonal genome-wide screenings in bat cells identify MTHFD1 as a target of broad antiviral therapy

D. E. Anderson, J. Cui, Q. Ye, B. Huang, W. Zu, J. Gong, W. Liu, S. Y. Kim, B. G. Yan, K. Sigmundsson, X. F. Lim, F. Ye, P. Niu, X. Zhou, W. Tan, , X. Tan

The paper identifies MTHFD1 as a target for broad antiviral therapy by screening bat cells with RNAi and CRISPR libraries against mumps and influenza viruses.

bioRxiv · Mar 29, 2020Microbiology

Genome-wide quantitative trait loci mapping on Verticilliumw

H. o. Rashid, P. Li, T. Chen, K. K. Palanga, W. Gong, Q. Ge, J. Gong, A. Liu, Q. Lu, L. Diouf, Z. Sarfraz, M. Jamshed, Y. Shi, Y. Yuan

This study identifies 53 QTLs associated with Verticillium wilt resistance in cotton using CSSLs and detects 32 novel QTL hotspot regions, providing a foundation for genetic analysis and breeding programs.

bioRxiv · Oct 1, 2019Plant Biology

Defining the microenvironment landscape of bladder cancer using highly multiplexed spatial genomic and proteomic analysis

J. Reeves, Z. Zhang, Z. K. Norgaard, D. M. Zhou, J. Gong, Y. Liang, S. Das, S. E. Warren, M. Korpal, M. L. Hoang, J. M. Beechem, P. Kumar, V. Rimkunas

The paper uses spatial genomic and proteomic analysis to explore how PPARG signaling is linked to immune cell exclusion in bladder cancer.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology