D. Singh

The paper shows acetylation of TDP-43 drives its phase separation into intranuclear spherical annuli with liquid properties, regulated by HSP70 chaperone activity and proteasome function.

The paper tests a 3D-cultured buffalo granulosa cell-based RT-LAMP colour reaction to detect dioxin toxicity in milk, finding AHR expression as a potential marker.

This study investigates the link between HER2 expression and CagA+ H. pylori in gastric cancer tissues, finding that CagA+ H. pylori may induce HER2 overexpression.

The paper identifies a novel CYP20A1 transcript isoform generated by Alu exaptation that functions as a miRNA sponge in human neurons.

The paper identifies Rph15, a resistance gene from wild barley, which provides broad-spectrum resistance to leaf rust and develops a diagnostic marker for its introgression into cultivated barley.

The paper identifies CD4+ follicular helper-like T cells as critical for enhancing anti-tumor CD8+ T cell responses and tumor growth inhibition.

The paper compares two bird populations to assess how photoperiod affects breeding latitude and reproductive timing, finding differences in critical photoperiod thresholds and migration distance.

This paper identifies a novel role of clathrin in stabilizing microtubules during mitosis by repurposing its adaptor interaction sites to recruit GTSE1, which inhibits MCAK and supports chromosome congression.

The paper evaluates how non-canonical guide RNAs and Cas9 variants affect DNA unwinding, finding that some combinations reduce off-target activity while maintaining on-target efficiency.

This study characterizes the DNA interrogation and product release kinetics of three Cpf1 orthologues using single-molecule fluorescence and biochemical assays, revealing differences from Cas9 in binding and cleavage requirements.

This study reveals how engineered Cas9 variants improve specificity by altering DNA unwinding dynamics and cleavage rates in response to mismatches.