Author

E. Dai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:scRNA-seq· 4 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

L. Wang· 4 shared G. Han· 3 shared A. E. Spira· 2 shared A. Sinjab· 2 shared B. Sepesi· 2 shared C. S. Stevenson· 2 shared E. R. Parra· 2 shared H. Kadara· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

L. Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD8 T-cell dysfunction is linked with CAR T-cell failure and can be mitigated by a non-alpha IL-2 agonist, pegenzileukin

P. K. Reville, I. N. Sheikh, A. Choi, E. Dai, J. Henderson, X. Li, E. Rojas, C. C. Le, C. Okwuchi, M. Devonish, R. Carrio, N. Pate, K. Malley, D. Bangari, J.-A. Givigan, , M. R. Green

The paper identifies dysfunctional CD8 CAR T-cells in rrLBCL tumors and shows that pegenzileukin mitigates this dysfunction, improving CAR T-cell responses.

bioRxiv · Aug 28, 2023 · PreprintImmunology

An atlas of epithelial cell states and plasticity in lung adenocarcinoma

G. Han, A. Sinjab, Z. Rahal, A. M. Lynch, W. Treekitkarnmongkol, Y. Liu, A. G. Serrano, J. Feng, K. Liang, K. Khan, W. Lu, S. Hernandez, Y. Liu, X. Cao, E. Dai, , H. Kadara

This study maps epithelial cell states and plasticity in lung adenocarcinoma using single-cell data, identifying KRT8+ alveolar intermediate cells linked to poor survival and tumorigenesis.

bioRxiv · May 13, 2022Cancer Biology

Immune microenvironment subtypes and association with tumor cell mutations and antigen expression in follicular lymphoma.

G. Han, Q. Deng, E. Dai, M. Dang, J. Ma, H. Yang, O. Kudryashova, M. Meerson, S. Isaev, N. Kotlov, K. Nomie, A. Bagaev, S. Parmar, F. Hagemeister, S. Ahmed, , M. R. Green

The paper identifies immune microenvironment subtypes in follicular lymphoma linked to tumor mutations and antigen expression, informing potential immunotherapeutic strategies.

bioRxiv · Apr 27, 2021 · PreprintCancer Biology

Resolving the spatial and cellular architecture of lung adenocarcinoma by multi-region single-cell sequencing

A. Sinjab, G. Han, W. Treekitkarnmongkol, K. Kobayashi, P. Brennan, M. Dang, D. Hao, R. Wang, E. Dai, H. Dejima, J. Zhang, E. Bogatenkova, B. Sanchez-Espiridion, K. Chang, D. R. Little, , H. Kadara

This study uses multi-region single-cell sequencing to map the spatial and cellular architecture of early-stage lung adenocarcinoma, revealing geospatial lineage evolution and potential therapeutic targets.

bioRxiv · Sep 4, 2020 · PreprintCancer Biology