Author

T. Nottoli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Bai· 3 shared A. A. Kocher· 1 shared A. Datye· 1 shared A. Du· 1 shared A. Kumar· 1 shared B. T. Goult· 1 shared C. Booth· 1 shared C. Liu· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioengineering

S. Bai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics

K. Tang, X. Zhou, S.-Y. Fang, E. Vandenbulcke, A. Du, J. Shen, H. Cao, J. Zhou, K. Chen, S. Xin, L. Zhou, S. H. Lin, M. Majety, X. Ling, S. Z. Lam, , S. Chen

bioRxiv · Mar 14, 2024 · PreprintBioengineering

Evolutionary innovation in conserved regulatory elements across the mammalian tree of life

S. Uebbing, A. A. Kocher, M. Baumgartner, Y. Ji, S. Bai, X. Xing, T. Nottoli, J. P. Noonan

The paper identifies accelerated evolution in conserved enhancer elements across mammals and links it to regulatory function turnover and developmental gene modifications.

bioRxiv · Jan 31, 2024Evolutionary Biology

Mechanosensing through talin 1 contributes to tissue mechanical homeostasis

M. V. Chanduri, A. Kumar, D. Weiss, N. Emuna, I. Barsukov, M. Shi, K. Tanaka, X. Wang, A. Datye, J. Kanyo, F. Collin, T. Lam, U. D. Schwarz, S. Bai, T. Nottoli, , M. A. Schwartz

This study shows that mutations in talin1 alter cellular stiffness sensing, leading to changes in ECM mechanical properties and aortic compliance.

bioRxiv · Sep 3, 2023 · PreprintCell Biology