J. Qi

This study shows BET bromodomain proteins drive inflammatory gene networks in cardiac fibroblasts, contributing to genetic dilated cardiomyopathy, and that JQ1, a BET inhibitor, reduces disease progression.

The paper models leukemia transcriptome dynamics in a state-space to identify critical points that predict disease development.

This study establishes a mouse orthodontic retention model and shows that longer retention and anti-c-Fms antibody reduce orthodontic relapse.

This paper introduces a relative Patlak plot method for dynamic PET that eliminates the need for early-time input function, enabling more efficient parametric imaging with equivalent clinical utility.

The paper identifies a potent and selective ROR1-targeting scFv, R11, and determines its structure bound to ROR1, showing its antitumor activity in vitro and in vivo.

The paper shows auxin signaling regulates cambium activity through specific transcription factors, influencing stem cell number and wood formation.