Author

J.-X. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:C. elegans· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2

Frequent Co-Authors

N. Pujol· 2 shared Y. Chen· 2 shared A. C. Cantrell· 1 shared B. Harding· 1 shared C. Li· 1 shared C. Taffoni· 1 shared C. Yan· 1 shared C.-Q. Liang· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

N. Pujol

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A long non-coding RNA LINC00094 regulates the transcriptional expression of lipid metabolism-related genes as a new member of core regulatory circuitry in esophageal squamous cell carcinoma

L. Peng, Q.-Y. Wang, J.-X. Chen, Y. Chen, R.-Y. Li, L.-D. Liao, W. Lin, C. Li, E.-M. Li, L. Xu

This paper identifies LINC00094 as a long non-coding RNA that forms a core regulatory circuitry with TCF3 and KLF5 to regulate lipid metabolism-related genes in esophageal squamous cell carcinoma.

bioRxiv · Jul 10, 2024 · PreprintCancer Biology

P53 Acetylation Exerts Critical Roles In Pressure Overload Induced Coronary Microvascular Dysfunction and Heart Failure

X. He, A. C. Cantrell, Q. A. Williams, W. Gu, Y. Chen, J.-X. Chen, H. Zeng

This study shows that preventing p53 acetylation improves coronary microvascular dysfunction and prevents heart failure in a mouse model of pressure overload.

bioRxiv · Feb 8, 2023 · PreprintPathology

Mettl3-mediated m6A modification of Fgf16 restricts cardiomyocyte proliferation during heart regeneration

F.-Q. Jiang, J.-X. Chen, W.-Y. Chen, W.-L. Zhao, G.-H. Song, C.-Q. Liang, Y.-M. Zhou, H.-L. Huang, R.-J. Huang, H. Zhao, K.-S. Park, Z. Ju, D. Cai, X.-F. Qi

This study shows that Mettl3-mediated m6A modification of Fgf16 limits cardiomyocyte proliferation and heart regeneration in mice.

bioRxiv · Feb 27, 2022Cell Biology

Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences.

X. Zhang, B. Harding, D. Aggad, D. Courtine, J.-X. Chen, N. Pujol, J. Ewbank

The paper investigates two fungal enterotoxins from Drechmeria coniospora and their distinct effects on the innate immune system of C. elegans.

bioRxiv · Nov 23, 2020Microbiology

CsHscB as a novel TLR2 agonist from carcinogenic liver fluke Clonorchis sinensis modulates host immune response

C. Yan, F. Fang, Y.-Z. Zhang, J. Wu, X. Dong, H.-L. Liu, C.-Y. Fan, Q. Yu, L. Wang, X.-Y. Li, Y. Wang, J.-X. Chen, R.-X. Tang, K.-Y. Zheng

The paper identifies CsHscB from Clonorchis sinensis as a TLR2 agonist that modulates macrophage activation and IL-10 production through TLR2-dependent mechanisms.

bioRxiv · Nov 29, 2019 · PreprintImmunology

Evolutionary plasticity in the innate immune function of Akirin

J. Polanowska, J.-X. Chen, J. Soule, S. Omi, J. Belougne, C. Taffoni, N. Pujol, M. Selbach, O. Zugasti, J. J. Ewbank

This study identifies conserved and divergent roles of Akirin in innate immune gene regulation across species, revealing lineage-specific adaptations in its functional partners.

bioRxiv · Dec 6, 2017Immunology