A Mechanically Resilient Soft Hydrogel Improves Drug Delivery for Treating Post-Traumatic Osteoarthritis in Physically Active Joints
N. Joshi, J. Yan, M. Dang, K. Slaughter, Y. Wang, D. Wu, T. Ung, V. Pandya, M. X. Chen, S. Kaur, S. Bhagchandani, H. Alfassam, J. Joseph, J. Gao, M. Dewani, , J. Ermann
This paper develops a mechanically resilient hydrogel for drug delivery in physically active joints, showing sustained release and reduced cartilage degeneration in a mouse model of post-traumatic osteoarthritis.
bioRxiv · May 16, 2024Bioengineering