Author

J. Karp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Gao· 3 shared J. Joseph· 3 shared J. N. Luo· 3 shared N. Joshi· 3 shared P. Shah· 3 shared C. Shukla· 2 shared E. Agus· 2 shared K. Slaughter· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersBioengineering

J. Gao

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Author profile →

5 papers

Recent·Most cited

A Mechanically Resilient Soft Hydrogel Improves Drug Delivery for Treating Post-Traumatic Osteoarthritis in Physically Active Joints

N. Joshi, J. Yan, M. Dang, K. Slaughter, Y. Wang, D. Wu, T. Ung, V. Pandya, M. X. Chen, S. Kaur, S. Bhagchandani, H. Alfassam, J. Joseph, J. Gao, M. Dewani, , J. Ermann

This paper develops a mechanically resilient hydrogel for drug delivery in physically active joints, showing sustained release and reduced cartilage degeneration in a mouse model of post-traumatic osteoarthritis.

bioRxiv · May 16, 2024Bioengineering

Ultra-Long-Term Delivery of Hydrophilic Drugs Using Injectable In Situ Cross-Linked Depots

S. Lee, S. Zhao, W. Jiang, X. Chen, L. Zhu, J. Joseph, E. Agus, H. B. Mary, S. Barooj, K. Slaughter, K. Cheung, J. N. Luo, C. Shukla, J. Gao, D. Lee, , N. Joshi

This paper develops an injectable platform for ultra-long-term hydrophilic drug delivery, achieving sustained release over six months in vivo.

bioRxiv · Nov 4, 2023 · PreprintBioengineering

A Drug-Free Pathogen Capture and Neutralizing Nasal Spray to Prevent Emerging Respiratory Infections

J. Joseph, H. M. Baby, J. R. Quintero, D. Kenney, Y. Mebratu, E. Bhatia, P. Shah, K. Swain, S. Kaur, X. L. Li, J. Mwangi, O. Snapper, R. Nair, E. Agus, S. Ranganathan, , N. Joshi

This paper introduces a drug-free nasal spray that captures and neutralizes respiratory pathogens, showing high efficacy in mice against influenza.

bioRxiv · Oct 2, 2023 · PreprintBioengineering

Daily transient coating of the intestine leads to weight loss and improved glucose tolerance

T. Lo, Y. Lee, C.-Y. Tseng, Y. Hu, C. Mantzoros, J. Karp, A. Tavakkoli

This study shows that daily administration of LuCI, an oral gut coating agent, leads to weight loss and improved insulin sensitivity in a rat model of diet-induced obesity.

bioRxiv · Jun 11, 2021Bioengineering

Cabozantinib unlocks efficient in vivo targeted delivery of neutrophil-loaded nanoparticles into murine prostate tumors

K. Chaudagar, N. Landon-Brace, A. Solanki, H. M. Hieromnimon, E. Hegermiller, W. Li, Y. Shao, D. Wilkins, K. Bynoe, X.-L. Li, J. Clohessy, S. Ullas, J. Karp, A. Patnaik

This study shows cabozantinib enhances neutrophil-mediated delivery of nanoparticles to prostate tumors in mice, leading to higher NP accumulation in the tumor microenvironment.

bioRxiv · Apr 13, 2020Cancer Biology