Author

N. J. Meyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Assay:flow cytometry· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. R. Weisman· 4 shared A. E. Baxter· 3 shared A. E. Vaughan· 3 shared A. Pattekar· 3 shared A. R. Greenplate· 3 shared C. A. G. Ittner· 3 shared D. Mathew· 3 shared J. Dougherty· 3 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersImmunology

A. R. Weisman

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation

G. Zhao, M. E. Gentile, L. Xue, C. V. Cosgriff, A. I. Weiner, S. Adams-Tzivelekidis, J. Wong, X. Li, S. Kass-Gergi, N. P. Holcomb, M. C. Basil, K. M. Steward, J. D. Planer, E. Cantu, J. D. Christi, , A. E. Vaughan

This study identifies SPARCL1 as a pro-inflammatory mediator secreted by endothelial cells that worsens viral pneumonia by promoting macrophage activation and is elevated in severe COVID-19 cases.

Nature Communications · May 18, 2024Peer-reviewedImmunology

Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19

S. A. Apostolidis, A. Sarkar, H. M. Giannini, R. R. Goel, D. Mathew, A. Suzuki, A. E. Baxter, A. R. Greenplate, C. Alanio, M. Abdel-Hakeem, D. A. Oldridge, J. R. Giles, J. E. Wu, Z. Chen, Y. J. Huang, , E. J. Wherry

This study identifies FcγRIIA and C5a-C5aR pathways as mediators of platelet hyperactivation in COVID-19 patients, showing their role in thrombotic complications.

Frontiers in Immunology · Mar 3, 2022Peer-reviewedImmunology

Human red blood cells express the RNA sensor TLR7 and bind viral RNA

L. M. Lam, R. L. Clements, K. A. Eckart, A. R. Weisman, A. E. Vaughan, N. Yehya, N. J. Meyer, K. A. Jurado, N. S. Mangalmurti

This study shows human red blood cells express TLR7 and bind viral RNA, suggesting a potential role in immune responses and RNA-based diagnostics.

bioRxiv · Jan 1, 2022 · PreprintImmunology

Red Blood Cells Function as DNA Sensors

M. Lam, S. Murphy, D. Kokkinaki, A. Venosa, S. Sherrill-Mix, C. Casu, S. Rivella, A. Weiner, J. Park, S. Shin, A. E. Vaughan, B. H. Hahn, A. R. Odom John, N. J. Meyer, C. A. Hunter, , N. S. Mangalmurti

The paper shows red blood cells detect and bind DNA, triggering immune responses during infections.

bioRxiv · Feb 11, 2021 · PreprintImmunology

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

D. Mathew, J. R. Giles, A. E. Baxter, A. R. Greenplate, J. E. Wu, C. Alanio, D. A. Oldridge, L. Kuri-Cervantes, M. B. Pampena, K. D'Andrea, S. Manne, Z. Chen, Y. J. Huang, J. P. Reilly, A. R. Weisman, , E. J. Wherry

The paper identifies distinct immunotypes in COVID-19 patients through high-dimensional cytometry, linking them to disease severity and potential therapeutic implications.

bioRxiv · May 20, 2020Immunology

Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection

L. Kuri-Cervantes, M. B. Pampena, W. Meng, A. M. Rosenfeld, C. A. G. Ittner, A. R. Weisman, R. Agyekum, D. Mathew, A. E. Baxter, L. Vella, O. Kuthuru, S. Apostolidis, L. Bershaw, J. Dougherty, A. R. Greenplate, , M. R. Betts

The paper identifies broad immune perturbations in severe COVID-19, including innate and adaptive immune cell changes and heterogeneity in B cell responses and antibody production.

bioRxiv · May 18, 2020 · PreprintImmunology