Deciphering drug response and phenotypic heterogeneity of cancer cells using gene ensembles of regulatory units defined by chromatin domains
N. Pandey, M. Sharma, A. Mathur, G. A. Nzelu, M. Hakimullah, I. P. Jha, O. Chandra, S. Mishra, J. Bhattacharya, A. Sharma, R. Foo, K. S. Sandhu, A. Mandoli, R. DasGupta, V. KUMAR
The paper analyzes the relationship between TAD activity and drug response in cancer cells and patients, finding stronger correlations with TADs than individual genes.
bioRxiv · Jan 15, 2023 · PreprintCancer Biology