Y. Bae

Phenotypic screens identify biologic regulators of nanoparticle uptake in diffuse midline glioma

The paper identifies biologic regulators of nanoparticle uptake in diffuse midline glioma using CRISPR screens and functional assays, finding CTNNB1 and pathway members as key modulators.

Epigenetic Dynamics in Meniscus Cell Migration and its Zonal Dependency in Response to Inflammatory Conditions: Implications for Regeneration Strategies

This study investigates how epigenetic mechanisms regulate meniscus cell migration under inflammation, revealing zonal differences and potential therapeutic targets.

Operator model for evolutionary dynamics

The paper introduces an operator model to represent evolutionary factors mathematically and demonstrates its application in simulating mutation accumulation under different regimes.

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic development

This study provides the first comprehensive gene expression profile of Plasmodium falciparum liver stages during in vivo development, revealing key metabolic and regulatory processes.

Survivin is a mechanosensitive cell cycle regulator in vascular smooth muscle cells

The paper identifies survivin as a mechanosensitive regulator of cell cycle progression in vascular smooth muscle cells under mechanical stress.

Survivin Regulates Intracellular Stiffness and Extracellular Matrix Production in Vascular Smooth Muscle Cells

This study shows survivin regulates intracellular stiffness and ECM production in VSMCs, linking it to arterial stiffness and vascular disease.

Rac rather than Rho drives the early transcriptional response to extracellular matrix stiffness and mediates repression of ATF3

The paper investigates the role of Rac and Rho in the transcriptional response to ECM stiffness and finds Rac drives the early response and represses ATF3.

Korean endemic species no more: on the occurrence of Pelophylax chosenicus in China

The paper surveys the distribution of Pelophylax chosenicus across Korea and China, finding it widespread in wetlands with a northernmost population in China.

Mitochondria-containing EVs Protect Brain Endothelial Cells and Reduce Mouse Brain Infarct Sizes

This paper shows that medium-to-large extracellular vesicles (m/lEVs) protect brain endothelial cells by transferring mitochondria and reducing brain infarct sizes in a mouse stroke model.

miRNA-34c suppresses osteosarcoma progression in vivo by targeting Notch and E2F

This study shows miR-34c suppresses osteosarcoma progression by targeting Notch and E2F pathways, improving survival in mouse models and correlating with better patient outcomes.

Development of A Decellularized Meniscus Matrix-Based Nanofibrous Scaffold for Meniscus Tissue Engineering

This paper develops a nanofibrous scaffold using decellularized meniscus matrix and synthetic polymers to enhance meniscus cell function and matrix production.

Mechanosensitive Expression of Lamellipodin Governs Cell Cycle Progression and Intracellular Stiffness

This study shows that ECM stiffness increases lamellipodin expression, which drives cell cycle progression and intracellular stiffness throughout the cell cycle.

Machine learning reveals heterogeneous responses to FAK, Rac, Rho, and Cdc42 inhibition on vascular smooth muscle cell spheroid formation and morphology

This study uses HETEROID to analyze how FAK, Rac, Rho, and Cdc42 inhibitors affect VSMC spheroid formation and morphology, revealing pathway-specific responses.

Loop-mediated isothermal amplification assay for Enterococcus sp., E. coli and S. aureus in chicken

The paper develops LAMP assays for detecting Enterococcus sp., E. coli, and S. aureus in chicken to diagnose bacterial chondronecrosis with osteomyelitis.

Deconvolution Of Subcellular Protrusion Heterogeneity And The Underlying Actin Regulator Dynamics From Live Cell Imaging

This paper introduces HACKS, a machine learning framework to analyze live cell imaging data and uncover subcellular protrusion heterogeneity and actin regulator dynamics.