S. Arnold

COA8 is a COX10-binding protein involved in the early biogenesis of cytochrome c oxidase

This study identifies COA8 as a COX10-binding protein essential for COX10 stability and catalytic activity in human cytochrome c oxidase biogenesis.

Structural rather than catalytic role for mitochondrial respiratory chain supercomplexes

This study shows that mitochondrial respiratory chain supercomplexes stabilize individual complexes under suboptimal conditions but do not enhance catalytic activity.

MRPS36 provides a missing link in the eukaryotic 2-oxoglutarate dehydrogenase complex for recruitment of E3 to the E2 core

The paper identifies MRPS36 as an essential component of the eukaryotic 2-oxoglutarate dehydrogenase complex, replacing the bacterial PSBD and providing structural insights into its organization.

Membrane curvature governs the distribution of Piezo1 in live cells

This study shows membrane curvature regulates Piezo1 distribution in live cells, with Piezo1 depletion from curved protrusions and enrichment in invaginations, and activation reduces filopodia formation.

Comparative assessment of the effects of bumped kinase inhibitors on early zebrafish embryo development and pregnancy in mice.

This study evaluates the effects of 15 bumped kinase inhibitors on zebrafish embryo development and mouse pregnancy, finding limited predictive value of zebrafish tests for pregnancy outcomes.