Membrane curvature governs the distribution of Piezo1 in live cells
S. Yang, X. Miao, S. Arnold, B. Li, A. T. Ly, H. Wang, M. Wang, X. Guo, M. M. Pathak, W. Zhao, C. D. Cox, Z. Shi
This study shows membrane curvature regulates Piezo1 distribution in live cells, with Piezo1 depletion from curved protrusions and enrichment in invaginations, and activation reduces filopodia formation.
bioRxiv · Jun 22, 2022Biophysics