Author

S. House

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

P. Mishra· 3 shared R. J. DeBerardinis· 3 shared N. P. Lesner· 2 shared S. D. Shelton· 2 shared X. Wang· 2 shared Z. Chen· 2 shared A. B. Aurora· 1 shared A. Bagrodia· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

P. Mishra

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis

S. D. Shelton, S. House, V. Ramesh, Z. Chen, T. Wei, X. Wang, C. B. Llamas, S. S. Venigalla, C. J. Menezes, Z. Zhao, J. G. Gill, R. J. DeBerardinis, S. J. Morrison, A. Tasdogan, P. Mishra

This study shows that pathogenic mtDNA mutations in melanoma cells reduce metastasis by limiting circulation entry, despite promoting tumor growth.

bioRxiv · Sep 1, 2023Cancer Biology

Mitochondrial metabolism in primary and metastatic human kidney cancers

D. Bezwada, R. J. DeBerardinis, N. P. Lesner, B. Brooks, H. S. Vu, Z. Wu, L. Cai, S. Kasitinon, S. Kelekar, F. Cai, A. B. Aurora, M. Patrick, A. Leach, R. Ghandour, Y. Zhang, , V. Margulis

This study investigates mitochondrial metabolism in kidney cancers, finding that primary tumors have suppressed mitochondrial function while metastases show enhanced TCA cycle labeling.

bioRxiv · Feb 6, 2023Cancer Biology

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

N. P. Lesner, X. Wang, Z. Chen, A. Frank, C. Menezes, S. House, S. D. Shelton, D. G. McFadden, J. Wansapura, R. J. DeBerardinis, P. Mishra

This study investigates the tissue-specific roles of mitochondrial complex I and IV in adult mouse liver, finding that complex I loss is tolerated while complex IV dysfunction causes metabolic and functional impairments.

bioRxiv · Jul 15, 2021Cell Biology

Gene flux and acid-imposed selection are the main drivers of antimicrobial resistance in broiler chicks infected with Salmonella enterica serovar Heidelberg

A. Oladeinde, Z. Abdo, M. O. Press, K. Cook, N. A. Cox, B. Zwirzitz, R. Woyda, S. M. Lakin, J. C. Thomas, T. Looft, D. E. Cosby, A. Hinton, J. Guard, E. Line, M. J. Rothrock, , C. Ritz

This study shows that antibiotic-resistant Salmonella can acquire resistance from gut commensals in antibiotic-free broiler chicks, driven by horizontal gene transfer and acidic selection pressure, suggesting antibiotic reduction alone may not limit resistance spread.

bioRxiv · Feb 25, 2021Microbiology