Y. Abe

Heart generation via blastocyst complementation in Mesp1/2-deficient mice

This study generates functional adult hearts in Mesp1/2-deficient mice using blastocyst complementation with pluripotent stem cells, showing successful derivation of all cardiovascular lineages from exogenous cells.

Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks

This study shows SART1 promotes DSB end resection in HR, cooperates with BRCA1 to counteract 53BP1/RIF1, and is required for BRCA1 recruitment to DSBs.

Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability

This study shows that structural flexibility of A2-17 peptide enhances its ability to penetrate cell membranes compared to its constrained variants.

Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane.

This study identifies LAZY1-LIKE proteins as gravity sensors in plant statocytes, showing their polar localization based on gravity direction.

Disentangling the complex gene interaction networks between rice and the blast fungus identifies a new pathogen effector

A comprehensive list of the replication promoters of Bunyavirales reveals a unique promoter structure in Nairoviridae differing from other virus families

The paper identifies a unique GC-rich promoter structure in Nairoviridae, distinguishing it from other Bunyavirales families, and provides a comprehensive list of replication promoters.

LncRNA Malat1 represses Th17 effector program by maintaining a critical bivalent super-enhancer and promotes intestinal inflammation

This study shows that lncRNA Malat1 restricts Th17 cell IL-17A production by regulating a bivalent super-enhancer, thereby controlling intestinal inflammation resolution.

Frequency of a nucleotide overhang at the 5' end of hemorrhagic fever mammarenavirus genomes in public sequence data

The paper examines the frequency of a 5' guanine overhang in mammarenavirus genomes and links it to their pathogenicity.

Quantitative Measurement of Diffusion-weighted Imaging Signal Using Expression-controlled Aquaporin-4 Cells: Comparative Study of 2-compartment and Diffusion Kurtosis Imaging Models

This study compares 2-compartment and diffusion kurtosis imaging models to assess how AQP4 expression affects diffusion-weighted imaging signal parameters in cell suspensions.

Characterization of human embryonic stem cells in animal component-free medium

This study shows that SEES2 ESCs can be stably cultured in an animal component-free medium for 60 days without losing their karyotype or differentiation potential.

Micromanipulation of amyloplasts with optical tweezers in Arabidopsis stems

The paper uses optical tweezers to manipulate amyloplasts in Arabidopsis stems and observes their interactions with vacuolar membranes, revealing biophysical responses to mechanical stimuli.

Safety assessment of a novel C-type natriuretic peptide derivative and the mechanism of bone- and cartilage-specific toxicity

This study assesses the safety of ASB20123, a C-type natriuretic peptide derivative, showing bone- and cartilage-specific toxicity linked to growth acceleration and identifying epiphyseal plate thickness and BMD as biomarkers.