Z. Chu

A precise IDMS-based method for absolute quantification of phytohemagglutinin, a major antinutritional component in common bean

This paper introduces an IDMS-based LC-MS/MS method for precise quantification of phytohemagglutinin in common beans, showing high linearity, sensitivity, recovery, and repeatability.

SART1 localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly

This study identifies SART1 as a mitosis-specific microtubule-associated protein that localizes to spindle poles and recruits PCM proteins for spindle assembly.

A breast cancer patient-derived xenograft and organoid platform for drug discovery and precision oncology

The paper develops patient-derived xenografts and organoids for breast cancer to enable drug screening and precision oncology, showing efficacy of an FDA-approved drug in a clinical case.

Human fecal microbiota is associated with colorectal cancer

This study analyzes fecal microbiota composition in CRC patients and identifies Fusobacterium as a potential biomarker for CRC screening in Chinese populations.

The Rpi-mcq1 resistance gene family recognizes Avr2 of Phytophthora infestans but is distinct from R2

The paper identifies a new family of Rpi genes in Solanum species that recognize the same effector AVR2 as the R2 gene family, showing two distinct R protein families can target the same pathogen effector.

Impaired Layer Specific Retinal Vascular Reactivity Among Diabetic Subjects

This study examines layer-specific retinal vascular reactivity in diabetic patients and finds impaired responses to oxygen and carbon dioxide in deep retinal layers.

Quantifying subclinical and longitudinal microvascular changes following episcleral plaque brachytherapy (EPB) using spectral-domain OCT angiography.

This study uses OCTA to detect microvascular changes after EPB, finding reduced capillary density and increased nonperfusion even without visible retinopathy.