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This study shows that flagellin FLiC enhances upland cotton resistance to Verticillium dahliae by inducing immune responses and modulating calcium, hydrogen peroxide, and nitric oxide pathways.

This paper develops three ex vivo skin culture models for HS to study molecular pathogenesis and drug efficacy.

This paper introduces HiLo microscopy for rapid, non-destructive lung adenocarcinoma pathology with high resolution and speed, comparable to gold-standard histology.

This study shows that cell stiffness and cytoskeletal regulators Rac and Rho influence complement-mediated injury in choroidal endothelial cells in early AMD.

This study identifies a β-catenin-NFκB-CFTR interactome in cholangiocytes that regulates inflammation and fibrosis during ductular reaction in liver disease.

This study uses single-nucleus RNA sequencing to analyze kidney tubule injury and repair in COVID-19 patients, identifying cell state transitions and reparative mechanisms.

This study shows that Bacteroides activates HSPCs in the BM during acute gut inflammation to promote tissue repair, but impairs HSC function in chronic inflammation and aging.

This study compares the pathogenicity and virus shedding of 13 lyssavirus isolates in a mouse model, revealing differences in clinical signs, survival, and astrocyte infection.

The paper develops Bmi-1/hTERT cell lines to model CFTR variants and shows that CC-90009 partially rescues W1282X-CFTR function while affecting sodium channel activity.

This study examines functional deficiencies in popliteal lymphatic vessels from TNF-Tg mice with inflammatory arthritis, showing reduced contraction and flow parameters that are partially reversible with NOS inhibition.

The paper analyzes genetic diversity and evolutionary dynamics of Begomoviruses causing papaya leaf curl disease in India, finding that mutation drives diversification more than recombination.

This study evaluates hemodynamic changes and biomarker levels in rats with sepsis induced by cecal ligation and puncture, finding that arterial blood pressure was not a reliable predictor of sepsis onset.

This study uses inverse probability weighting to analyze morphometric and echocardiographic data in Cavalier King Charles Spaniels to identify associations with mitral valve disease severity.

This study identifies hyperconcentrated mucus as a unifying mechanism for submucosal gland and superficial airway dysfunction in cystic fibrosis.

This study investigates the molecular interactions between Candidatus Liberibacter asiaticus and the gut of its vector Diaphorina citri, identifying gene expression changes and potential targets for disease management.

This study shows that IL-6 promotes PSAT1 expression and serine metabolism in TSC2-deficient cells, linking IL-6 to mTORC1 hyperactivity and potential therapeutic targets.

This study examines sex differences in cardio-pulmonary pathology in SARS-CoV-2 infected and Trypanosoma cruzi co-infected mice, showing sex-specific effects on adipose tissue and inflammation.

This study shows mitochondrial-targeted antioxidants reduce oxidative stress and metabolic issues in PKD mouse models, improving disease progression and restoring metabolic pathways.

This study investigates SAMD1's role in LDL retention and atherosclerosis by analyzing its distribution in mouse models and testing inhibitors' effects on lesion growth.