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This study identifies 28 genes associated with efferocytosis that are differentially expressed in oral lichen planus, suggesting defective or delayed clearance of apoptotic cells.

The paper develops and validates simple immunohistochemical classifiers for bladder cancer subtyping using routine and non-routine antibody assays, achieving high accuracy in identifying molecular subtypes.

This study shows Brsk2 amplifies parasympathetic signals to promote type 2 diabetes by enhancing β-cell insulin secretion in obese mice and associates human BRSK2 variants with metabolic disorders.

The paper develops a novel mouse model for scar tissue formation in the abdominal muscle wall without artificial factors, showing collagen-rich granulation tissue similar to human scars.

This study uses mixed-effects machine learning to predict colon cancer metastasis by analyzing spatially localized immuno-oncology markers in tumor tissue.

This study identifies distinct and heterogeneous amyloid beta strains in Down syndrome patients with advanced Alzheimer's disease, suggesting unique pathogenic mechanisms compared to sporadic Alzheimer's.

This study shows hypertension in non-human primates leads to gut barrier dysfunction and microbial translocation, altering the gut microbiome.

This study identifies SEMA3C as a key driver of liver fibrosis by enhancing TGF-β signaling in hepatic stellate cells.

The paper reports the complete genome of a carbapenem-resistant E. coli ST410 strain isolated from Singapore reservoir water, harboring the blaNDM-5 gene.

This study identifies transcriptomic changes in cardiac fibroblasts associated with cardiac microthrombi in fatal COVID-19 through single nuclei RNA sequencing and clinical analyses.

This study evaluates the resistance of 10 Moroccan cactus genotypes to Dactylopius opuntiae, identifying antixenosis and antibiosis effects in some genotypes.

This study uses single-nucleus RNA-seq and spatial transcriptomics to identify lineage-specific regulatory changes and candidate therapeutic targets in hypertrophy cardiomyopathy.

This paper develops a convolutional neural network to screen body fluid cytology smears for malignant cells, achieving high sensitivity and specificity but with room for improvement in detecting scattered cells and reducing false positives.

This paper develops a transgenic zebrafish reporter to measure proteinuria, demonstrating its utility in detecting kidney disease models and drug responses.

This study shows that OPN deficiency reduces inflammation and fibrosis in the prostate after E. coli infection in mice.

This study identifies BcPTP1 as a phytotoxic effector secreted by Botrytis cinerea during late infection, which induces cell death and promotes lesion spreading.

This meta-analysis finds that OCD patients show longer stop-signal reaction times, indicating impaired response inhibition, with greater deficits in older individuals.

TaBln1 negatively regulates wheat resistance to stripe rust by reducing Ca2+ influx through its interaction with TaCaM3 on the plasma membrane.

The paper examines the rational use of plant protection products in a vineyard to manage fungal diseases while minimizing environmental and health risks.

This study shows that Phyllanthus niruri extract reduces malaria parasite numbers by blocking erythrocyte invasion and modulates host immune responses, protecting against cerebral malaria in mice.