Author

A. Arora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Bioengineering· 3 Cancer Biology· 3 Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Research Focus:cell type annotation· 7 Research Focus:clustering· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Organism:mouse· 3

Frequent Co-Authors

V. Viasnoff· 5 shared A. Sweeney· 3 shared C. Fu· 3 shared S. Mallidi· 3 shared V. Kumar· 3 shared A. Kalita· 2 shared B. Arasi· 2 shared D. Dutta· 2 shared

Activity by Year

2019-2025 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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5 shared papersCell Biology

V. Viasnoff

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Author profile →

14 papers

Recent·Most cited

Vascular regional analysis unveils differential responses to anti-angiogenic therapy in pancreatic xenografts through macroscopic photoacoustic imaging

A. Sweeney, M. Xavierselvan, A. Langley, P. Solomon, A. Arora, S. Mallidi

This study uses macroscopic photoacoustic imaging to analyze vascular regional changes in pancreatic xenografts during anti-angiogenic therapy, identifying differential responses through vascular regional analysis.

Theranostics · Jan 27, 2025Peer-reviewedBioengineering

Plasma membrane order maps functional diversity in immune cells

L. A. Andronico, C. O. Gurdap, A. Arora, F. Ragaller, P. A. Sandoz, Y. Jiang, S. Giatrellis, L. de Boer, V. Carannante, S. Iskrak, J. Mikes, M. Buggert, A. Osterborg, B. Onfelt, A. S. Klymchenko, , E. Sezgin

The paper identifies immune cell subsets with distinct functional behaviors based on plasma membrane order using biophysical profiling and transcriptome analysis.

bioRxiv · Jan 15, 2024Biophysics

E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes.

C. Fu, F. Dilasser, S.-Z. Lin, M. Karnat, A. Arora, H. Rajendiran, H. T. Ong, N. M. Hoon, S. W. Phow, T. Hirashima, M. Sheezt, J.-F. Rupprecht, S. Tlili, V. Viasnoff

bioRxiv · Dec 4, 2023 · PreprintCell Biology

Impact of ectopic calcification on vascular oxygenation in placental dysfunction models: Simultaneous in vivo assessment with multi-parametric ultrasound and photoacoustic imaging

S. A. Edwards, A. Correia-Branco, D. Sankepalle, A. Arora, A. Sweeney, P. Solomon, M. C. Wallingford, S. Mallidi

bioRxiv · Dec 4, 2023 · PreprintBioengineering

Cortical ductility governs cell-cell adhesion mechanics

A. Arora, M. S. Rizvi, G. Grenci, F. Dilasser, C. Fu, M. Ganguli, S. Vaishnavi, K. Paramsivam, S. Budnar, I. Noodstra, A. Yap, V. Viasnoff

This study introduces a new method to measure energy dissipation during cell-cell junction rupture and shows that cortical tension and shape relaxation time determine whether junctions behave ductile or brittle.

bioRxiv · Nov 28, 2023 · PreprintCell Biology

Ultrasound-guided Photoacoustic image Annotation Toolkit in MATLAB (PHANTOM) for preclinical applications

A. Sweeney, A. Arora, S. Edwards, S. Mallidi

PHANTOM is a MATLAB toolkit for fluence-compensation in photoacoustic imaging, validated with phantoms and preclinical models.

bioRxiv · Nov 7, 2023Bioengineering

Leveraging RAS-mSIN1 Interaction to Selectively Inhibit mTORC2 Employing Competitive RAS Binding Peptide: Implications in Breast Cancer Metastasis

J. Miyan, N. Kumar, S. A. Malik, Moinuddin, U. M. Akif, J. Kumar, R. Hameed, P. Dubey, M. Singh, J. Vishwakarma, S. Tripathi, R. Ramachandran, M. I. Siddiqi, V. Kumar, M. L. B. Bhatt, , S. Bhadauria

The paper withdraws a manuscript due to incomplete experiments and requests that it not be cited as a reference.

bioRxiv · May 6, 2023Cancer Biology

An intrinsic alkalization circuit turns on mntP-riboswitch under manganese stress in Escherichia coli

A. Kalita, R. K. Mishra, V. Kumar, A. Arora, D. Dutta

The paper shows that manganese stress in E. coli activates a circuit involving ammonia production and cytoplasmic alkalization, enhancing mntP-riboswitch activation to improve manganese tolerance.

bioRxiv · Aug 31, 2022Biochemistry

ORP5/8 AND MIB/MICOS LINK ER-MITOCHONDRIA AND INTRAMITOCHONDRIAL CONTACTS FOR NON-VESICULAR TRANSPORT OF PHOSPHATIDYLSERINE

V. F. Monteiro-Cardoso, L. Rochin, A. Arora, A. Houcine, E. Jaaskelainen, A. M. Kivela, C. Sauvanet, R. Le Bars, E. Marien, J. Dehairs, J. Neveu, N. El Khallouki, E. Santonico, J. V. Swinnen, D. Tareste, , F. Giordano

The paper identifies ORP5/8 and MIB/MICOS complexes as mediators of non-vesicular phosphatidylserine transport between ER and mitochondria via membrane contact sites.

bioRxiv · May 25, 2022Cell Biology

Harbingers of Aggressive Prostate Cancer: Precision Oncology Case Studies

J. Cyrta, D. Prandi, A. Arora, D. H. Hovelson, A. Sboner, A. Rodriguez, T. Fedrizzi, H. Beltran, D. R. Robinson, A. Gopalan, L. True, P. Nelson, B. D. Robinson, J. M. Mosquera, S. Tomlins, , M. Rubin

This study identifies molecular features of primary prostate cancer and their relation to metastasis using genomic and histopathological analysis.

bioRxiv · Nov 30, 2021 · PreprintCancer Biology

Free spermidine evokes superoxide radicals that manifest toxicity

V. Kumar, R. K. Mishra, D. Ghose, A. Kalita, A. Prakash, G. Mitra, A. Arora, D. Dutta

The paper shows that excess free spermidine generates superoxide radicals, causing toxicity in bacteria lacking the SpeG enzyme, while SpeG enables tolerance by neutralizing spermidine.

bioRxiv · Sep 4, 2021Biochemistry

Cooperative regulation of adherens junction elongation through Epidermal Growth Factor Receptor (EGFR) activation.

C. Fu, A. Arora, W. Engl, M. Sheetz, V. Viasnoff

The paper shows that EGFR activation increases adherens junction elongation speed without affecting final size in suspended cell aggregates.

bioRxiv · May 25, 2021Biophysics

A Method to sort heterogenous cell populations based on migration in 2D and 3D environments

A. Arora, J. L. Galeano, M. Z. Myaing, B. Arasi, R. Y.-J. Huang, R. DasGupta, M. Biro, V. Viasnoff

This paper introduces a method to sort migratory cancer and immune cells based on their spontaneous migration in 2D and 3D environments, revealing enhanced cytotoxicity in enriched migratory cytotoxic T lymphocytes.

bioRxiv · May 6, 2020 · PreprintCell Biology

Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

A. Ravasio, M. Z. Myaing, S. Chia, A. Arora, A. Sathe, E. Y. Cao, C. Bertocchi, A. Sharma, B. Arasi, V. Y. Chung, A. C. Green, T. Z. Tan, Z. Chen, H. T. Ong, N. G. Iyer, , V. Viasnoff

The paper develops a single-cell assay to analyze EphA receptor clustering in cancer cells, revealing its persistence through division and association with migration and drug resistance.

bioRxiv · May 10, 2019Cancer Biology