Author

A. Bah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Biophysics· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Chakraborty· 2 shared A. Dutta· 2 shared H. Hehnly· 2 shared J. D. Forman-Kay· 2 shared J. L. Henty-Ridilla· 2 shared L. G. Dettori· 2 shared L. Gonzalez· 2 shared P. Sung· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

A. Chakraborty

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Uncovering the molecular interactions underlying MBD2 and MBD3 phase separation

M. Nicole, T. Phan, J. L. Henty-Ridilla, Y. C. Kim, J. Mittal, A. Bah

This study investigates the molecular interactions driving phase separation in MBD2 and MBD3 proteins, revealing distinct mechanisms despite their structural similarity.

bioRxiv · Apr 29, 2024Biochemistry

Delineating Structural Propensities of the 4E-BP2 Protein via Integrative Modelling and Clustering

T. E. Tsangaris, S. Smyth, G.-N. W. Gomes, Z. H. Liu, M. Milchberg, G. A. Wasney, A. Bah, J. D. Forman-Kay, C. C. Gradinaru

This study uses integrative modelling and clustering to analyze the structural propensities of 4E-BP2 in its non-phosphorylated and five-phosphorylated forms, revealing insights into intrachain interactions and conformational states.

bioRxiv · Jun 20, 2023 · PreprintBiophysics

ABI1 regulates transcriptional activity of Androgen Receptor by novel DNA and AR binding mechanism

B. A. Porter, X. Li, N. Arya, F. Zhang, S. H. Y. Kung, L. Fazli, H. Zarni Oo, Y. Li, K. Marincin, K. Kukkonen, H. Urhonen, M. A. Ortiz, A. P. Kemraj, E. Corey, X. Dong, , L. Kotula

This paper identifies ABI1 as an epigenetic regulator of transcriptional homeostasis in AR-driven cancers through novel DNA and AR binding mechanisms.

bioRxiv · May 26, 2023 · PreprintCancer Biology

Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock

D. Tariq, N. Maurici, B. Bartholomai, S. Chandrasekaran, J. C. Dunlap, A. Bah, B. R. CRANE

This study investigates how phosphorylation, disorder, and phase separation regulate the behavior of Frequency (FRQ) in the fungal circadian clock of Neurospora crassa.

bioRxiv · Nov 3, 2022Biochemistry

FMRP directly interacts with R-loop and shows complex interplay with the DHX9 helicase

A. Chakraborty, A. Dutta, L. G. Dettori, J. Li, L. Gonzalez, X. Xue, H. Hehnly, P. Sung, A. Bah, W. Feng

The paper was withdrawn due to duplicate submission and is not intended for citation.

bioRxiv · Jul 10, 2022Biochemistry

Multisite Phosphorylation and Binding Alter Conformational Dynamics of the 4E-BP2 Protein

S. Smyth, Z. Zhang, A. Bah, T. Tsangaris, J. Dawson, J. D. Forman-Kay, C. Gradinaru

This study uses single-molecule techniques to analyze how phosphorylation and binding alter the conformational dynamics of the intrinsically disordered 4E-BP2 protein.

bioRxiv · Jan 14, 2022Biophysics

FMRP DIRECTLY INTERACTS WITH R-LOOP AND SHOWS COMPLEX INTERPLAY WITH THE DHX9 HELICASE

A. Chakraborty, A. Dutta, L. G. Dettori, L. Gonzalez, X. Xue, H. Hehnly, P. Sung, A. Bah, W. Feng

This study shows FMRP directly binds R-loops and inhibits DHX9 helicase activity, preventing R-loop accumulation and genome instability in FXS.

bioRxiv · Apr 21, 2021 · PreprintBiochemistry

Inhibition of ITK differentiates GVT and GVHD in allo-HSCT

M. Karimi, M. Mammadli, W. Huang, R. Harris, A. Sultana, Y. Cheng, W. Tong, J. Pu, T. Gentile, J. L. Henty-Ridilla, S. Dsouza, Q. Yang, A. August, A. Bah

This paper shows that inhibiting ITK in donor T cells reduces GVHD while preserving GVT effects in allo-HSCT using murine models and a novel peptide inhibitor.

bioRxiv · Jul 15, 2020 · PreprintImmunology