Author

C. Trapnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Pathology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Organism:human· 4 Assay:scRNA-seq· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2

Frequent Co-Authors

D. F. Read· 2 shared L. Carter· 2 shared A. Bourdon· 1 shared A. Etemadi· 1 shared A. Favor· 1 shared A. Murison· 1 shared A. N. Murray· 1 shared A. Patel· 1 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPathology

D. F. Read

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Dystrophin deficiency impairs cell junction formation during embryonic myogenesis

E. Mozin, E. Massourides, V. Mournetas, C. Lievre, A. Bourdon, D. L. Jackson, J. S. Packer, J. Seong, C. Trapnell, C. Le Guiner, O. Adjali, C. Pinset, D. L. Mack, J.-B. Dupont

This study shows that dystrophin deficiency disrupts cell junction formation during embryonic myogenesis in human pluripotent stem cells.

bioRxiv · Dec 5, 2023 · PreprintPathology

Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing

T. Itkin, S. Houghton, R. Schreiner, Y. Lin, C. Badwe, V. Voisin, A. Murison, N. Seyedhassantehrani, K. B. Kaufmann, L. Garcia-Prat, G. T. Booth, F. Geng, Y. Liu, J. M. Gomez-Salinero, J.-H. Shieh, , S. Rafii

The paper identifies Fli-1's role in regulating HSC activation during regenerative hematopoiesis by enabling niche signaling and functional recovery.

bioRxiv · Mar 27, 2023 · PreprintCell Biology

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

N. I. Edman, R. L. Redler, A. Phal, T. Schlichthaerle, S. R. Srivatsan, A. Etemadi, S. An, A. Favor, D. Ehnes, Z. Li, F. Praetorius, M. Gordon, W. Yang, B. Coventry, D. R. Hicks, , D. Baker

This study designs synthetic oligomeric ligands to modulate FGFR signaling and shows their impact on vascular cell fate decisions.

bioRxiv · Mar 14, 2023Bioengineering

Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis

Y. Hasegawa, J. M. Franks, Y. Tanaka, Y. Uehara, D. F. Read, C. Williams, S. Srivatsan, L. B. Pitstick, N. M. Nikolaidis, C. M. Shaver, H. Wu, J. C. Gardner, A. R. Osterburg, J. J. Yu, E. J. Kopras, , F. X. McCormack

The paper investigates silica-induced pulmonary fibrosis in mice, finding that silica triggers osteoclast-like differentiation of macrophages and monocytes, contributing to lung injury and fibrosis.

bioRxiv · Feb 17, 2023Pathology

Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication

E. R. Vanderwall, K. A. Barrow, L. M. Rich, D. F. Read, C. Trapnell, O. Oghenemega, S. F. Ziegler, T. S. Hallstrand, M. P. White, J. S. Debley

The paper compares the IFN response to SARS-CoV-2 and HRV-16 in airway epithelial cells and shows that HRV-16 induces a stronger IFN response and reduces SARS-CoV-2 replication.

bioRxiv · Nov 20, 2021Immunology

Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma

H. Feldman, C. Toledo, S. Arora, P. Hoellerbauer, P. Corrin, L. Carter, M. Kufeld, H. Bolouri, R. Basom, J. Delrow, J. McFaline-Figueroa, C. Trapnell, S. Pollard, A. Patel, C. Plaisier, P. Paddison

The paper identifies a quiescent-like state, Neural G0, in human neural stem cells and gliomas using scRNA-seq, linking it to tumor aggressiveness and survival.

bioRxiv · Feb 16, 2020 · PreprintCell Biology

IL2 enhances ex-vivo expanded regulatory T cell persistence after adoptive transfer

S. N. Furlan, K. Singh, C. Lopez, V. Tkachev, D. Hunt, J. Hibbard, K. M. Betz, B. R. Blazar, C. Trapnell, L. S. Kean

This study shows that adding IL2 to rapamycin increases the persistence of ex-vivo expanded regulatory T cells in non-human primates, doubling their numbers in peripheral blood.

bioRxiv · Oct 15, 2019Immunology