Author

D. A. Wolf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

G. Tian· 3 shared Y. Cheng· 3 shared C. Hu· 2 shared H. Duan· 2 shared Y. Lin· 2 shared A. Rosa Campos· 1 shared C.-C. Yang· 1 shared F. Li· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

G. Tian

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content

H. Duan, S. Zhang, Y. Zarai, R. Oellinger, Y. Wu, L. Sun, C. Hu, G. Tian, R. Rad, Y. Cheng, T. Tuller, D. A. Wolf

The paper identifies eIF3k as a regulator of ribosome content in cancer by showing its depletion increases global translation and stress resistance through repression of RPS15A synthesis.

The EMBO Journal · May 8, 2023Peer-reviewedCell Biology

NDC80 status pinpoints mitotic kinase inhibitors as emerging therapeutic options in clear cell renal cell carcinoma

C. Hu, W. Lin, K. Zhao, G. Tian, X. Kong, G. Luo, D. A. Wolf, Y. Cheng

The paper identifies NDC80 as a predictor of ccRCC progression and shows that NDC80-high tumors are sensitive to mitotic kinase inhibitors.

bioRxiv · Mar 7, 2023Cancer Biology

eIF3 associates with 80S ribosomes to promote translation elongation, mitochondrial homeostasis, and muscle health

Y. Lin, F. Li, L. Huang, H. Duan, J. Fang, L. Sun, X. Xing, G. Tian, Y. Cheng, X. Yang, D. A. Wolf

This study shows eIF3 interacts with 80S ribosomes to enhance early translation elongation of mRNAs involved in mitochondrial and membrane functions, critical for muscle health.

bioRxiv · Dec 22, 2019Cell Biology

Crosstalk between eIF2α and eEF2 phosphorylation pathways optimizes translational arrest in response to oxidative stress

M. Sanchez, Y. Lin, C.-C. Yang, P. McQuary, A. Rosa Campos, P. Aza Blanc, D. A. Wolf

This study shows that oxidative stress causes translational arrest through eEF2 phosphorylation, not eIF2, and reveals crosstalk between eIF2 and eEF2 pathways in mouse cells.

bioRxiv · Jul 5, 2019Cell Biology