E. Holmes

Contrasting dynamics of two incursions of low pathogenicity avian influenza virus into Australia

The paper compares two avian influenza virus incursions in Australia, showing contrasting evolutionary dynamics between H4 and H10 viruses.

Connecting Thiamine Availability to the Microbial Community Composition in Chinook Salmon Spawning Habitats of the Sacramento River Basin

The paper investigates thiamine and its metabolites (dTRCs) in Sacramento River spawning habitats, linking microbial communities to thiamine availability for Chinook salmon.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

The paper identifies critical transcription factor regulons in FLT3-ITD+ AML by analyzing gene regulatory networks and shows their necessity for AML growth.

Microbe-derived indole tunes organ-function and links microbe metabolites to biological ageing

This study shows that indole, a gut microbe metabolite, is essential for maintaining organ function and metabolic homeostasis, and its deficiency leads to multiorgan decline and accelerated biological ageing.

A switch in jaw form-function coupling during the evolution of mammals

This paper shows that crown mammals have diverse jaw shapes but stereotyped jaw stiffness, which is genetically based and allows resistance to deformation despite dietary diversity.

Host age shapes virome abundance and diversity in birds

The paper examines how host age affects virome abundance and diversity in birds, finding higher viral diversity and abundance in juveniles compared to adults.

Arabidopsis UGT76B1 glycosylates N-hydroxy-pipecolic acid and inactivates systemic acquired resistance in tomato

This study shows that Arabidopsis UGT76B1 glycosylates NHP, reducing systemic acquired resistance in tomato by altering defense priming.

Identification and evolution of avian endogenous foamy viruses

The paper identifies endogenous foamy viruses in two stork species, showing independent integration events in birds and expanding the known taxonomic distribution of foamy viruses.

Novel hepatitis D-like agents in vertebrates and invertebrates

The paper identifies HDV-like viruses in non-human vertebrates and invertebrates, showing they share genomic features with HDV but are not associated with hepadnavirus infection.

Conservation of N-hydroxy-pipecolic acid-mediated systemic acquired resistance in crop plants

The paper shows N-hydroxy-pipecolic acid (NHP) mediates systemic acquired resistance in tomato and pepper, suggesting engineering NHP production could enhance crop disease resistance.

Virome heterogeneity and connectivity in waterfowl and shorebird communities

The paper characterizes viromes of waterfowl and shorebirds, revealing 27 viral species, 24 novel, and highlighting virome connectivity and heterogeneity across host species.

N-hydroxy-pipecolic acid is a mobile signal that induces systemic disease resistance in Arabidopsis

This study identifies N-hydroxy-pipecolic acid as a mobile signal inducing systemic disease resistance in Arabidopsis by showing its role in SAR signal transduction and pathogen resistance.