Author

J. Demeter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Assay:proteomics· 5 Research Focus:cell type annotation· 4 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

P. K. Jackson· 6 shared N. A. Mooney· 3 shared D. R. McIlwain· 2 shared G. L. Barlow· 2 shared G. P. Nolan· 2 shared A. Banuelos· 1 shared A. C. Hinken· 1 shared A. M. Boutelle· 1 shared

Activity by Year

2019-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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6 shared papersCell Biology

P. K. Jackson

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

The Mettl3 epitranscriptomic writer amplifies p53 stress responses

N. Raj, M. Wang, J. A. Seoane, N. A. Moonie, J. Demeter, A. M. Kaiser, A. M. Boutelle, A. S. Mulligan, C. Moffatt, C. Curtis, H. Chang, P. K. Jackson, L. D. Attardi

This paper identifies Mettl3 as a p53-interacting protein that stabilizes p53 and enhances its tumor suppressive functions through both protein stabilization and m6A modification of p53 pathway transcripts.

bioRxiv · Oct 21, 2021Cancer Biology

Virus-Dependent Immune Conditioning of Tissue Microenvironments

S. Jiang, C. N. Chan, X. Rovira-Clave, H. Chen, Y. Bai, B. Zhu, E. McCaffrey, N. F. Greenwald, C. Liu, G. L. Barlow, J. L. Weirather, K. Busman-Sahay, M. Nekorchuk, M. Terry, S. Younger, , G. P. Nolan

The paper develops PANINI-MIBI to analyze DNA, RNA, and protein in SIV-infected tissues, revealing IL10 upregulation and macrophage polarization linked to viral latency.

bioRxiv · May 21, 2021Immunology

Divergent molecular signatures of regeneration and fibrosis during wound repair

S. Mascharak, H. E. desJardins-Park, M. Januszyk, K. Chen, M. F. Davitt, J. Demeter, D. Henn, M. Griffin, C. A. Bonham, D. S. Foster, N. A. Mooney, R. Cheng, P. K. Jackson, D. C. Wan, G. C. Gurtner, M. T. Longaker

This study identifies divergent molecular signatures of regeneration and fibrosis during wound repair using multimodal analysis.

bioRxiv · Dec 17, 2020 · PreprintCell Biology

Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion

P. K. Jackson, S. K. Kim, C.-T. Wu, K. Hilgendorf, R. Bevacqua, Y. Hang, J. Demeter

The paper identifies ciliary GPCRs in pancreatic islet cells that regulate insulin and glucagon secretion, with FFAR4 and PTGER4 as key targets for diabetes therapy.

bioRxiv · Oct 21, 2020Physiology

Multiple domains in ARHGAP36 regulate PKA degradation and Gli activation

P. R. Nano, T. Kudo, N. A. Mooney, J. Ni, J. Demeter, P. K. Jackson, J. K. Chen

This study identifies how multiple domains in ARHGAP36 regulate PKA degradation and Gli activation through structural and functional analysis.

bioRxiv · May 14, 2020 · PreprintCell Biology

Ciliation of muscle stem cells is critical to maintain regenerative capacity and is lost during aging

A. R. Palla, K. I. Hilgendorf, A. V. Yang, J. P. Kerr, A. C. Hinken, J. Demeter, P. Kraft, N. A. Mooney, N. Yucel, P. K. Jackson, H. M. Blau

This study identifies ciliary Hedgehog signaling as critical for muscle stem cell regeneration, showing that restoring it in aged mice improves muscle repair.

bioRxiv · Mar 20, 2020Cell Biology

Mass spectrometry analysis of mouse hematopoietic stem cells and their progenitors reveals differential expression within and between proteome and transcriptome throughout adult and aged hematopoiesis

B. W. Zaro, J. J. Noh, V. L. Mascetti, J. Demeter, B. M. George, M. Zukowska, G. S. Gulati, R. Sinha, R. M. Morganti, A. Banuelos, A. Zhang, P. K. Jackson, I. L. Weissman

The paper reports a proteomics resource analyzing protein expression in mouse adult and aged hematopoietic stem cells and their progenitors, revealing differential expression and gene regulation.

bioRxiv · Nov 9, 2019Cell Biology

Coordinated cellular neighborhoods orchestrate antitumoral immunity at the colorectal cancer invasive front

C. M. Schürch, S. S. Bhate, G. L. Barlow, D. J. Phillips, L. Noti, I. Zlobec, P. Chu, S. Black, J. Demeter, D. R. McIlwain, N. Samusik, Y. Goltsev, G. P. Nolan

The paper identifies cellular neighborhoods in colorectal cancer that correlate with antitumoral immunity and patient survival.

bioRxiv · Aug 24, 2019Immunology