Author

J. Ouyang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Immunology· 2 Biophysics· 1 Cancer Biology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

F. Li· 2 shared H. Liu· 2 shared H. Zhang· 2 shared J. Liu· 2 shared L. Wang· 2 shared M. Li· 2 shared M. Xing· 2 shared X. Li· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

F. Li

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Caspase-8-mediated CYLD cleavage boots LPS-induced endotoxic shock.

J. Liu, M. Li, M. Xing, H. Liu, X. Wu, L. Wang, X. Li, X. Zhao, J. Ouyang, Y. Zhang, F. Li, Q. Xie, Y. Tan, Y. Wang, Y. Xie, , H. Zhang

This study identifies Caspase-8-mediated CYLD cleavage as a mechanism promoting LPS-induced endotoxic shock and reveals CP25 as a potential biomarker.

bioRxiv · Apr 3, 2024 · PreprintImmunology

Hormonal plasticity to food restriction is heritable

J. Ouyang, A. Lendvai

This study shows glucocorticoid responsiveness to food restriction is heritable in house sparrows, with moderate heritability and environmental variance playing a larger role under restricted food conditions.

bioRxiv · Sep 29, 2023 · PreprintEvolutionary Biology

Excessive apoptosis of naïve T cells resulting hyperactivation as a cause of mammalian aging

L. Wang, X. Zhang, H. Zhang, K. Lu, M. Li, X. Li, J. Ouyang, X. Zhao, X. Wu, J. Liu, M. Xing, H. Liu, Y. Zhang, Y. Tan, F. Li, , B. Zhou

This study shows that excessive apoptosis in naïve T cells causes hyperactivation and accelerates aging in mice, suggesting T-cell changes are a cause of aging.

bioRxiv · Feb 24, 2023 · PreprintImmunology

LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers

C. Li, M. U. Syed, A. Nimbalkar, Y. Shen, C. Fraser, Z. Inde, X. Qin, J. Ouyang, J. Kreuzer, S. E. Clark, G. E. Kelley, E. Hensley, A. Oh, M. Walcott, R. Morris, , A. N. Hata

This study shows LKB1 suppresses JNK-dependent stress signaling in KRAS-mutant lung cancers, revealing a therapy-induced vulnerability that could improve KRAS-targeted therapies.

bioRxiv · Sep 29, 2022 · PreprintCancer Biology

The great tit HapMap project: a continental-scale analysis of genomic variation in a songbird

L. G. Spurgin, M. Bosse, F. Adriaensen, T. Albayrak, C. Barboutis, E. Belda, A. Bushuev, J. Cecere, A. Charmantier, M. Cichon, N. J. Dingemanse, B. Doligez, T. Eeva, K. E. Erikstad, V. Federov, , Sheld

This study analyzes genomic variation across 647 great tit individuals to understand how environmental and demographic factors shape genetic diversity and differentiation.

bioRxiv · Dec 9, 2020Evolutionary Biology

Dependence of fluorodeoxyglucose (FDG) uptake on cell cycle and dry mass: a single-cell study using a multi-modal radiography platform

Y. Sung, M.-A. Tetrault, K. Takahashi, J. Ouyang, G. Pratx, M. Normandin, G. El Fakhri

This study measures [18F]FDG uptake, dry mass, and cell cycle phase in single HeLa cells to investigate their relationship, finding higher FDG uptake in S, G2, or M phases and a positive correlation with dry mass.

bioRxiv · Jun 12, 2019Biophysics

Effects of sublethal concentrations and application concentration of SYP-9625 on Tetranychus cinnabarinus (Boisduval) and its natural enemy, Neoseiulus californicus (McGregor)

J. Ouyang, Y. Tian, C. Jiang, Q. Yang, H. Wang, Q. Li, No

This study evaluates the sublethal effects of SYP-9625 on Tetranychus cinnabarinus and its impact on the predatory mite Neoseiulus californicus, showing reduced pest population growth and minimal effect on the predator.

bioRxiv · Jun 6, 2018Zoology