Author

L. Kuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:Arabidopsis· 2 Assay:DNA methylation· 2 Research Focus:ecology & biodiversity· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

A. Ciota· 2 shared A. Payne· 2 shared L. Kramer· 2 shared M. Onyango· 2 shared A. Bukreyev· 1 shared A. E. Pottash· 1 shared A. Jeyaram· 1 shared A. Vigneron· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Ciota

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Combinatorial microRNA loading into extracellular vesicles for anti-inflammatory therapy

A. E. Pottash, D. Levy, A. Jeyaram, L. Kuo, S. M. Kronstadt, W. Chao, S. M. Jay

The paper investigates the anti-inflammatory effects of loading multiple miRNAs into extracellular vesicles and identifies a combination of miR-146a, miR-155, and miR-223 as the most effective.

bioRxiv · Jul 13, 2022 · PreprintBioengineering

A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an AAV hACE2 Mouse Model and non-human primates

F. Guirakhoo, L. Kuo, J. Peng, J. H. Huang, B. Kuo, F. Lin, Y.-J. Liu, Z. Liu, G. Wu, S. Ding, K.-L. Hou, J. Cheng, V. Yang, H. Jiang, J. Wang, , C. Y. Wang

This paper describes a multitope protein-peptide vaccine candidate, UB-612, that is immunogenic and prevents lung infection in animal models, with ongoing clinical trials.

bioRxiv · Nov 30, 2020 · PreprintImmunology

Potential for transmission of Elizabethkingia anophelis by Aedes albopictus and the role of microbial interactions in Zika virus competence

M. Onyango, A. Payne, J. Stout, C. Dieme, L. Kuo, A. Ciota, L. Kramer

The paper demonstrates that Elizabethkingia anophelis is present in Aedes mosquito saliva and inhibits Zika virus replication in midguts, suggesting vector-borne transmission potential and a novel transmission barrier for arboviruses.

bioRxiv · Mar 27, 2020 · PreprintMicrobiology

Increased temperatures reduce the vectorial capacity of Aedes mosquitoes for Zika virus

m. Onyango, S. Bialosuknia, A. Payne, N. Mathias, L. Kuo, A. Vigneron, M. DeGennaro, A. Ciota, l. kramer

This study shows that increased temperatures reduce the vectorial capacity of Aedes mosquitoes for Zika virus, with greater effects on Ae. aegypti than Ae. albopictus.

bioRxiv · Jul 14, 2019Microbiology

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

P. S. Kwon, S. Ren, S.-J. Kwon, M. E. Kizer, L. Kuo, F. Zhou, F. Zhang, D. Kim, K. Fraser, L. D. Kramer, N. C. Seeman, J. S. Dordick, R. J. Linhardt, J. Chao, X. Wang

The paper designs a DNA nanostructure that recognizes and inhibits dengue virus through precise spatial arrangement of aptamers, enabling sensitive and rapid sensing and inhibition.

bioRxiv · Apr 13, 2019Bioengineering

Assessing Combinability of Phylogenomic Data using Bayes Factors

S. Neupane, K. Fucikova, L. A. Lewis, L. Kuo, M.-H. Chen, P. Lewis

The paper uses Bayes Factors to assess phylogenomic data combinability, showing their effectiveness in detecting phylogenetic incongruence and calibrating results with an empirical dataset.

bioRxiv · Jan 19, 2018Evolutionary Biology