N. Mukherjee

SASH1 interacts with TNKS2 and promotes human melanocyte stem cell maintenance

This study identifies SASH1 as a regulator of melanocyte stem cell maintenance, showing that the S519N variant disrupts its function and links to pigmentation disorders.

A 3D microtumour system that faithfully represents ovarian cancer minimal residual disease

This paper develops a 3D microtumour system that mimics ovarian cancer minimal residual disease, showing it responds to chemotherapy and reflects molecular signatures of MRD.

Virus-Dependent Immune Conditioning of Tissue Microenvironments

The paper develops PANINI-MIBI to analyze DNA, RNA, and protein in SIV-infected tissues, revealing IL10 upregulation and macrophage polarization linked to viral latency.

Destructive fishing - A ubiquitously used but vague term? Usage and impacts across academic research, media and policy

This study examines the usage and impacts of the term 'destructive fishing' across academic, media, and policy sources from 1976-2020, revealing regional variations and calls for a unified definition.

Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19

This study integrates plasma proteomics and single-cell immune features to classify COVID-19 severity and identify biological signatures of disease progression.

Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics

This study uses single-cell transcriptomics and protein profiling to analyze EBOV infection in rhesus monkeys, revealing changes in immune cell dynamics and viral/host gene expression.

Expression of Toll like Receptor 4 in the ductal epithelial cells of the Breast tumor microenvironment is correlated with the invasiveness of the tumor

The paper investigates TLR4 expression in breast tumors and finds it correlates with invasiveness and lymph node involvement, with differential effects in TP53 wild-type and mutant cells.

Insights from two decades of the Student Conference on Conservation Science

This study analyzes 3,245 SCCS conference applications to show increased focus on human-nature benefits and social science integration in tropical field research by early-career conservationists.

Azadirachta indica (A. Juss.) reduces circulating Dirofilaria immitis microfilariae in vivo

This study evaluates the effectiveness of ethanolic extract of Azadirachta indica leaves in reducing circulating Dirofilaria immitis microfilariae in dogs, showing significant reduction with no toxic effects.

Intracellular anti-leishmanial effect of Spergulin-A, a triterpenoid saponin of Glinus oppositifolius

This paper evaluates the anti-leishmanial activity of Spergulin-A, a triterpenoid saponin from Glinus oppositifolius, showing potent intracellular efficacy against Leishmania donovani.