Author

P. Bjorkman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Assay:proteomics· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:clustering· 2

Frequent Co-Authors

F. Muecksch· 3 shared F. Schmidt· 3 shared T. Hatziioannou· 3 shared A. Cho· 2 shared A. Gazumyan· 2 shared C. Barnes· 2 shared C. Gaebler· 2 shared C. O. Barnes· 2 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

F. Muecksch

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses

N. Catanzaro, Z. Wu, C. Fan, A. Schaefer, B. Yount, P. Bjorkman, R. S. Baric, M. C. Letko

The paper identifies ACE2 as a receptor for HKU5 coronaviruses from Pipistrellus abramus bats and investigates receptor tropism across merbecovirus clades.

bioRxiv · Mar 13, 2024 · PreprintMicrobiology

Rapid Identification of Neutralizing Antibodies against SARS-CoV-2 Variants by mRNA Display

S. Tanaka, C. A. Olson, C. O. Barnes, W. Higashide, M. Gonzales, J. Taft, A. Richardson, M. Martin-Fernandez, D. Bogunovic, P. N. P. Gnanapragasam, P. Bjorkman, P. R. Spilman, K. Niazi, S. Rabizadeh, P. Soon-Shiong

This study uses mRNA display to identify and engineer neutralizing antibodies against SARS-CoV-2 variants, revealing binding modes and demonstrating their effectiveness against mutations in the spike protein.

bioRxiv · Sep 14, 2021Immunology

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

C. A. Jette, A. A. Cohen, P. N. P. Gnanapragasam, F. Muecksch, Y. E. Lee, K. E. Huey-Tubman, F. Schmidt, T. Hatziioannou, P. D. Bieniasz, M. C. Nussenzweig, A. P. West, J. R. Keeffe, P. Bjorkman, C. O. Barnes

The paper identifies two class 4 anti-RBD antibodies from COVID-19 donors that broadly neutralize zoonotic sarbecoviruses and SARS-CoV-2 variants with high potency.

bioRxiv · Apr 23, 2021Immunology

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

I. Ullah, J. Prevost, M. S. Ladinsky, H. Stone, M. Lu, S. P. Anand, G. Beaudoin-Bussieres, K. Symmes, M. Benlarbi, S. Ding, R. Gasser, C. Fink, Y. Chen, A. Tauzin, G. Goyette, , P. D. Uchil

This study uses live imaging to show that neutralizing antibodies against SARS-CoV-2 need both Fab and Fc functions to effectively prevent and resolve infection in mice.

bioRxiv · Mar 22, 2021Immunology

Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies

F. Muecksch, Y. Weisblum, C. Barnes, F. Schmidt, D. Schaefer-Babajew, J. Lorenzi, A. Flyak, A. DeLaitsch, K. Huey-Tubman, S. Hou, C. Schiffer, C. Gaebler, Z. Wang, J. Da Silva, D. Poston, , P. Bieniasz

This study examines how somatic mutations in SARS-CoV-2 antibodies affect their neutralization potency, breadth, and resistance to escape mutations across six antibody lineages.

bioRxiv · Mar 7, 2021 · PreprintMicrobiology

In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission

K. A. Haugh, M. S. Ladinsky, I. Ullah, R. Pi, A. Gilardet, P. Kumar, P. Bjorkman, W. Mothes, P. D. Uchil

This study uses in vivo imaging to show that Siglec-1/CD169 on sentinel macrophages facilitates retrovirus transmission through multiple routes.

bioRxiv · Oct 20, 2020Microbiology

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals

D. F. Robbiani, C. Gaebler, F. Muecksch, J. Cetrulo Lorenzi, Z. Wang, A. Cho, M. Agudelo, C. Barnes, S. Finkin, T. Hagglof, T. Oliveira, C. Viant, A. Hurley, K. Millard, R. Kost, , Nuss

The paper analyzes antibody responses in convalescent individuals, finding low neutralizing titers but rare potent RBD-specific antibodies with broad antiviral potential.

bioRxiv · May 13, 2020Immunology