T. Meyer

The lnc-FANCI-2 intrinsically restricts RAS signaling in HPV16-infected cervical cancer

This study identifies lnc-FANCI-2 as a regulator of RAS signaling in HPV16-infected cervical cancer, showing its role in lesion progression and patient survival.

Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling

The paper investigates JAK recruitment specificity and promiscuity in cytokine-receptor signaling, finding that JAKs can interchangeably bind to receptors, leading to cell type-specific signaling pleiotropy.

Microbial community organization during anaerobic pulp and paper mill wastewater treatment

The paper analyzes microbial community organization in anaerobic wastewater treatment plants using amplicon sequencing and operating data to identify relationships between microbial populations and operational conditions.

Differential functional coupling in Gp130-JAK complexes expands the plasticity of the interleukin-6 signaling axis

The paper investigates how different JAKs in Gp130 signaling complexes lead to distinct STAT activation profiles and signaling outcomes.

Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation

This study shows oncogenic Ras-ERK signalling alters cell division orientation by affecting actomyosin contractility and cell-substrate interactions during mitotic rounding and respreading.

Structural mechanism for bi-directional actin crosslinking by T-plastin

Cryo-EM, biochemical, and cellular studies reveal how the crosslinking protein T-plastin bridges actin filaments in two opposing orientations.

Drug-free nasal spray as a barrier against SARS-CoV-2 infection: safety and efficacy in human nasal airway epithelia

This study tests a nasal spray (AM-301) for safety and efficacy against SARS-CoV-2 infection in human nasal epithelial models, finding it safe and significantly reduces viral titer.

Cdt1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis

The paper shows Cdt1 inhibits CMG helicase to prevent DNA synthesis during early S phase, separating origin licensing from DNA synthesis to avoid re-replication.

Surfactin stimulated by pectin molecular patterns and root exudates acts as a key driver of Bacillus-plant mutualistic interaction

This paper shows that Bacillus velezensis produces surfactin in response to pectin and root exudates, which enhances biofilm formation, motility, and plant immunity.

Chelator sensing and lipopeptide interplay mediates molecular interspecies interactions between soil bacilli and pseudomonads

The paper investigates molecular interactions between Bacillus velezensis and Pseudomonas, showing how chelator sensing and lipopeptides influence competitive outcomes in the rhizosphere.

Intravital imaging reveals cell cycle-dependent satellite cell migration during muscle regeneration.

This study uses intravital imaging to show that ERK promotes satellite cell migration during muscle regeneration by facilitating the G1/S transition and enhancing migration speed in the S/G2 phase through CDK2.

Evidence for dual targeting of Arabidopsis plastidial glucose-6-phosphate transporter GPT1 to peroxisomes via the ER

The paper shows GPT1 in Arabidopsis is dual-targeted to plastids and peroxisomes via the ER, explaining its unique functions compared to GPT2.

Measuring stepwise binding of a thermally fluctuating particle to a cell membrane without labeling

This paper demonstrates a label-free technique to detect stepwise binding events of particles to cell membranes by analyzing thermal fluctuations.

Membrane proximal F-actin restricts local membrane protrusions and directs cell migration

The paper shows that local decreases in membrane proximal F-actin density direct membrane protrusions and cell migration.

A parallel cell-cycle entry pathway with inverted G1 signaling and alternate point of no return

The paper identifies an alternate cell-cycle entry pathway with inverted G1 signaling and a new point of no return, demonstrated through single-cell microscopy in cell lines and mice.

Solid state anaerobic digestion of mixed organic waste: the synergistic effect of food waste addition on the destruction of paper and cardboard

This study evaluates solid-state anaerobic digestion of mixed organic waste, showing that adding food waste significantly increases methane production from paper and cardboard.

Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models

This paper shows that papillomavirus can be transmitted through blood and cause infections in animal models, suggesting blood transfusion as a potential route for HPV infection and cancer in humans.