Author

R. Hoh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Assay:flow cytometry· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:clustering· 2

Frequent Co-Authors

S. G. Deeks· 7 shared J. N. Martin· 3 shared J. Neidleman· 3 shared N. R. Roan· 3 shared R. Thomas· 3 shared X. Luo· 3 shared J. D. Kelly· 2 shared J. D. Siliciano· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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7 shared papersImmunology

S. G. Deeks

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Author profile →

7 papers

Recent·Most cited

Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2

K. Yin, M. J. Peluso, X. Luo, R. Thomas, M.-G. Shin, J. Neidleman, A. Andrew, K. Young, T. Ma, R. Hoh, K. Anglin, B. Huang, U. Argueta, M. Lopez, D. Valdivieso, , N. R. Roan

This study identifies T cell dysregulation, inflammation, and mis-coordinated adaptive immune responses in Long COVID patients compared to non-LC individuals.

bioRxiv · Feb 9, 2023Immunology

Markers of Fungal Translocation Are Elevated During Post-Acute Sequelae of SARS-CoV-2 Infection and Induce NF-κB Triggered Inflammation.

L. B. Giron, M. Peluso, J. Ding, G. Kenny, N. F. Zilberstein, J. Koshy, K. Y. Hong, H. Rasmussen, G. Miller, F. Bishehsari, R. A. Balk, J. N. Moy, R. Hoh, S. Lu, A. R. Goldman, , M. Abdel-Mohsen

This study identifies elevated fungal translocation markers in PASC patients, which induce NF-κB inflammation through Dectin-1 signaling.

bioRxiv · Apr 12, 2022 · PreprintMicrobiology

Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells from HIV+ Controllers and Non-Controllers

A. F. George, X. Luo, J. Neidleman, R. Hoh, P. Vohra, R. Thomas, M.-G. Shin, M. J. Lee, C. A. Blish, S. G. Deeks, W. C. Greene, S. A. Lee, N. R. Roan

This study compares T and NK cell phenotypes in blood and lymph nodes of HIV+ controllers and ART-treated individuals, finding distinct cellular features in lymphoid tissues.

bioRxiv · Oct 27, 2021 · PreprintImmunology

Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo

F. R. Simonetti, H. Zhang, G. P. Soroosh, J. Duan, K. Rhodehouse, A. L. Hill, S. A. Beg, K. McCormick, H. Raymond, C. L. Nobles, J. Everett, K. J. Kwon, J. A. White, J. Lai, J. B. Margolick, , R. F. Siliciano

This study links antigen responsiveness, proviral sequences, integration sites, and TCRβ sequences to show antigen-driven clonal selection maintains HIV-1 persistence in CD4+ T cells.

bioRxiv · Dec 1, 2020Microbiology

The Atlas of the In Vivo HIV CD4 T Cell Reservoir

J. Neidleman, X. Luo, J. Frouard, G. Xie, F. Hsiao, T. Ma, V. Morcilla, A. Lee, S. Telwatte, R. Thomas, W. Tamaki, B. Wheeler, R. Hoh, P. Vohra, J. Milush, , N. R. Roan

The paper develops a method to trace latently-infected HIV CD4 T cells to their original states using CyTOF, revealing the reservoir's conserved yet tissue-specific composition and enabling isolation of unstimulated latent cells.

bioRxiv · Jun 27, 2020Immunology

TCF-1 regulates the stem-like memory potential of HIV-specific CD8+ T cells in elite controllers

R. L. Rutishauser, C. D. T. Deguit, J. Hiatt, F. Blaeschke, T. L. Roth, L. Wang, K. Raymond, C. E. Starke, J. C. Mudd, W. Chen, C. Smullin, R. Matus-Nicodemos, R. Hoh, M. Krone, F. M. Hecht, , P. W. Hunt

The paper shows TCF-1 enhances HIV-specific CD8+ T cell expansion and memory properties in elite controllers.

bioRxiv · Jan 7, 2020 · PreprintImmunology

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

D. I. S. Rosenbloom, P. Bacchetti, M. Stone, X. Deng, R. J. Bosch, D. D. Richman, J. D. Siliciano, J. W. Mellors, S. G. Deeks, R. G. Ptak, R. Hoh, S. M. Keating, M. Dimapasoc, M. Massanella, J. Lai, , Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group

This study assesses the precision and repeatability of HIV-1 latent reservoir size measurements using QVOA across labs and storage conditions, finding assay variability and supporting frozen storage.

bioRxiv · Jun 6, 2018Microbiology