Y. Ishida

ILC2s navigate tissue redistribution during infection using stage-specific S1P receptors

This study shows that ILC2s use different S1P receptors at distinct stages to migrate during infection, highlighting a shared vascular network for lymphocyte movement.

Sensitization with an allogeneic MHC class I molecule induces anti-tumor immunity in the absence of PD-1 in mice

This study shows that overexpressing an allogeneic MHC-I molecule on tumor cells can induce anti-tumor immunity in PD-1 knockout mice, even without PD-1 signaling.

Granulomatous inflammatory responses are elicited in the liver of PD-1 knockout mice by de novo genome mutagenesis

This study shows that PD-1 knockout mice with genome mutations develop liver granulomatous inflammation, supporting PD-1's role in suppressing autoimmune responses to neoantigens.

Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhi hepatic macrophages

The paper shows that microbiome ssRNA activates TLR13 in hepatic macrophages to drive tissue-protective responses, leading to resistance against acute liver injury in Rnaset2-/- mice.

NF-κB Decoy ODN-Loaded Poly lactic-co-glycolic Acid Nanospheres Inhibit Alveolar Ridge Resorption

This study investigates the therapeutic effect of NF-κB decoy ODN-loaded PLGA nanospheres in reducing alveolar ridge resorption after tooth extraction in rats.

Circulating mast cell progenitors migrate to atopic dermatitis-like skin then adapt locally

The paper identifies BM-derived mast cell progenitors in AD-like skin that adapt to CTMC phenotypes through local proliferation and integrinβ7 downregulation.

Nasal delivery of single-domain antibodies improve symptoms of SARS-CoV-2 infection in an animal model

This paper shows nasal delivery of a camelid single-domain antibody reduces SARS-CoV-2 titers in hamsters without weight loss or cytokine induction.

Whole-genome sequence analysis of mutations in rice plants regenerated from zygotes, mature embryos, and immature embryos

The paper analyzes whole-genome sequences of rice plants regenerated from different embryonic sources to assess somaclonal variation and mutation rates.

Pivotal involvement of the CX3CL1-CX3CR1 axis for the recruitment of M2-TAMs in skin carcinogenesis

The paper investigates the role of the CX3CL1-CX3CR1 axis in skin carcinogenesis, finding that it promotes tumor-associated macrophage recruitment and function, contributing to cancer progression.