Author

A. Gaitas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Bioengineering· 1 Biophysics· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Gong· 6 shared Q. Chang· 5 shared Y. Qiu· 4 shared C. Zhou· 3 shared J. Bei· 3 shared Y. Jin· 3 shared Y. Liu· 3 shared Z. Su· 3 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersCell Biology

B. Gong

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Exosomally targeting microRNA23a ameliorates microvascular endothelial barrier dysfunction following rickettsial infection

C. Zhou, J. Bei, Y. Qiu, Q. Chang, E. Nyong, J. Yang, B. Krishnan, K. Khanipov, Y. Jin, X. Fang, A. Gaitas, B. Gong

This study shows that exosomal miR23a from rickettsial-infected endothelial cells disrupts BMEC barrier function by targeting ZO-1, and that anti-miR23a exosomes can restore barrier integrity.

bioRxiv · Mar 25, 2022Cell Biology

AFM Microfluidic Cantilevers as Weight Sensors for Single Cell Mass Measurements

C.-c. Chien, J. Jiang, T. Li, B. Gong, A. Gaitas

This paper introduces microfluidic cantilevers for single-cell mass measurement, achieving sub-nanogram sensitivity and demonstrating improved performance with polymer materials.

bioRxiv · Feb 21, 2022Biophysics

Host EPAC1 modulates rickettsial adhesion to vascular endothelial cells via regulation of ANXA2 Y23 phosphorylation

Z. Su, T. Shelite, Y. Qiu, Q. Chang, M. Wakamiya, J. Bei, X. He, C. Zhou, Y. Liu, A. Gaitas, T. Saito, B. Gong

This study investigates how EPAC1 regulates rickettsial adhesion to endothelial cells by modulating ANXA2 Y23 phosphorylation, using in vivo models and FluidFM.

bioRxiv · Apr 20, 2021Pathology

Endothelial exosome plays functional role during rickettsial infection

Y. Liu, C. Zhou, Z. Su, Q. Chang, Y. Qiu, J. Bei, A. Gaitas, J. Xiao, A. Drelich, K. Khanipov, Y. Jin, G. Golovko, T. Berelli Saito, B. Gong

This study investigates the role of Rickettsia-infected endothelial cell-derived exosomes in causing barrier dysfunction in brain microvascular endothelial cells, identifying miR-23a and miR-30b as key regulators.

bioRxiv · Nov 16, 2020Microbiology

Establishing correlation of axial and vertical force of cardiac artificial tissue using a novel micromachined sensor

A. Gaitas, F. Stillitano, I. Turnbull

The paper develops a micromachined sensor to measure axial and vertical forces in cardiac tissue and establishes their correlation, supporting vertical measurements as an alternative to tissue-based assessments.

bioRxiv · Sep 16, 2020 · PreprintBioengineering

EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammation

J. Xiao, B. Zhang, Z. Su, Y. Liu, T. R. Shelite, Q. Chang, P. Wang, A. Bukreyev, L. Soong, Y. Jin, T. Ksiazek, A. Gaitas, S. L. Rossi, J. Zhou, M. Laposata, , B. Gong

This study shows EPAC1 regulates vWF secretion from endothelial cells during inflammation via the PI3K/eNOS pathway, with implications for thrombosis control.

bioRxiv · Sep 4, 2020 · PreprintCell Biology

Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

X. He, A. Drelich, Q. Chang, D. Gong, Y. Zhou, Y. Qu, S. Yu, Y. Yang, J. Qian, Y. Qiu, S.-J. Tang, A. Gaitas, T. Ksiazek, Z. Xu, M. Wakamiya, , B. Gong

This study shows that EPAC1 promotes ANXA2 translocation to endothelial cell surfaces, enhancing plasminogen to plasmin conversion and fibrinolysis.

bioRxiv · Oct 1, 2017Cell Biology