B. Zhu

This paper introduces a drug discovery platform called SPEED that uses epitope editing to screen small molecules for altering antibody-epitope interactions and validates its application for Aβ species.

This paper introduces subHMM, a hidden Markov model to estimate subclone regions, genotypes, and clonal proportions in tumor cells, applied to renal cell carcinoma data.

This study uses RNA-seq to analyze Xanthomonas oryzae pv. oryzicola's response to H2O2, revealing horizontal gene transfer's role in its oxidative stress response.

The paper introduces RpsA mutations Δ438A and D123A into M. tuberculosis to confirm their role in pyrazinamide resistance.

This study shows that Pseudomonas aeruginosa inhibits growth of Streptococcus species by producing siderophores that compete for iron.

This paper introduces the pencil method to detect oscillations in gene transcription, revealing new 12-hour oscillations and confirming biological independence of circadian rhythms.

This study identifies drugs that enhance pyrazinamide's anti-persister activity by screening a clinical drug library against M. tuberculosis cultures enriched with persisters.