Author

G. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Y. Zhang· 2 shared A. C. Tan· 1 shared A. J. Sanderup· 1 shared A. Jain· 1 shared A. Schambach· 1 shared A. Takano· 1 shared B. Qin· 1 shared B. Wang· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Y. Zhang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dearth of smoking-induced mutations in NSRO-driven non-small-cell lung cancer despite smoking exposure

C.-Y. Huang, N. Jiang, M. Shen, G. Lai, A. C. Tan, A. Jain, S. P. Saw, M.-K. Ang, Q. S. Ng, D. W.-T. Lim, R. Kanesvaran, E.-H. Tan, W. L. Tan, B.-H. Ong, K. L. Chua, , S. G. Rozen

The paper examines genomic and transcriptomic changes in NSRO-driven NSCLCs in smokers and non-smokers, finding no smoking-induced mutations but higher transcriptomic cell cycle activity in smokers.

bioRxiv · Jul 4, 2023 · PreprintCancer Biology

A SI3-sigma; arch stabilizes cyanobacteria transcription initiation complex

L. Shen, G. Lai, L. You, J. Shi, X. Wu, M. Puiu, Z. Gu, Y. Feng, Y. Yuzenkova, Y. Zhang

The paper reports cryo-EM structures of cyanobacterial transcription initiation complexes and identifies an SI3-{sigma} arch that stabilizes the RNAP-promoter DNA open complex, essential for transcription initiation.

bioRxiv · Oct 6, 2022Biochemistry

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

L. Han, X. Wei, C. Liu, G. Volpe, Z. Zhuang, X. Zou, Z. Wang, T. Pan, Y. Yuan, X. Zhang, P. Fan, P. Guo, Y. Lai, Y. Lei, X. Liu, , Z. Liu

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

bioRxiv · Dec 13, 2021Cell Biology

Diagnostic value of galactomannan in bronchoalveolar lavage fluid for chronic respiratory disease with pulmonary aspergillosis

G. Lai, C. Zeng, J. Mo, W. Song, p. Xu

This study evaluates the diagnostic value of bronchoalveolar lavage fluid galactomannan (BALF GM) for pulmonary aspergillosis in chronic respiratory disease, finding an optimal cut-off value of 0.485 with high sensitivity and specificity.

bioRxiv · Aug 9, 2019Microbiology