Author

M. Kuang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

F. You· 2 shared X. Wang· 2 shared Y. Zhao· 2 shared C. Huang· 1 shared C. Liao· 1 shared D. Duda· 1 shared D. Kuang· 1 shared F. Wang· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

F. You

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Distinct Single-cell Immune Ecosystems Distinguish True and De Novo HBV-related Hepatocellular Carcinoma Recurrences

S. Chen, C. Huang, G. Liao, H. Sun, Y. Xie, J. Wang, M. He, H. Hu, Z. Dai, X. Ren, X. Zeng, Q. Zeng, G. Zhang, C. Liao, W. Xie, , M. Kuang

This study identifies distinct immune ecosystems in true and de novo HBV-related HCC recurrences using single-cell and bulk RNA-sequencing, revealing differences in T cell phenotypes and immune interactions that may inform immunotherapy strategies.

bioRxiv · Jun 2, 2022Immunology

Accelerated mass transfer from frozen thin films during thin-film freeze-drying

J.-L. Wang, M. Kuang, H. Xu, R. O. Williams, Z. Cui

This study demonstrates that thin-film freeze-drying (TFFD) significantly accelerates mass transfer compared to conventional freeze-drying, preserving bacterial viability and enabling efficient powder production.

bioRxiv · Apr 16, 2022 · PreprintPharmacology & Toxicology

Collateral cleavage of 28s rRNA by RfxCas13d causes death of mice

Y. Li, J. Xu, X. Guo, Z. Li, L. Cao, S. Liu, Y. Guo, G. Wang, Y. Luo, Z. Zhang, X. Wei, Y. Zhao, T. Liu, X. Wang, H. Xia, , F. You

This study shows that RfxCas13d causes mouse death by collateral cleavage of 28s rRNA, highlighting biosafety concerns for CRISPR-Cas13 systems.

bioRxiv · Jan 17, 2022 · PreprintBioengineering

SARS-CoV-2 spike protein interacts with and activates TLR4

Y. Zhao, M. Kuang, X. Wang, F. You

This study identifies SARS-CoV-2 spike protein as a direct activator of TLR4 signaling in immune cells, leading to sepsis-related inflammation.

bioRxiv · Dec 18, 2020Immunology