Author

D. Pearce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Ecology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Saha· 2 shared E. Takagi· 2 shared A. Manis· 1 shared A. Prakash· 1 shared B. Henson· 1 shared C. Gleason· 1 shared C. Li· 1 shared C. Nowotny· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

B. Saha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Coordinated Regulation of Renal Glucose Reabsorption and Gluconeogenesis by mTORC2 and Potassium

J. Demko, B. Saha, E. Takagi, A. Manis, R. Weber, D. Pearce

This study shows that mTORC2 and dietary potassium coordinate renal glucose reabsorption and gluconeogenesis through independent mechanisms, with implications for diabetes management.

bioRxiv · Jun 22, 2024Physiology

A video-rate hyperspectral camera for monitoring plant health and biodiversity

L. J. Brooks, D. Pearce, K. Kwok, N. Jawade, M. Qi, E. Fenollosa, D. Beker, J. Whicker, K. Davis, R. Salguero-Gomez, R. Wang, S. Chappell

This paper introduces a video-rate hyperspectral camera for monitoring plant health and biodiversity, demonstrating its utility in chlorophyll detection and ecological studies.

bioRxiv · Jan 18, 2024 · PreprintEcology

Structural features of mTORC2 that control substrate-specific activities.

Z. Yu, J. Chen, E. Takagi, F. Wang, X. Liu, L.-M. Jourbert, B. Saha, C. Gleason, M. Jin, C. Li, C. Nowotny, D. Agard, Y. Cheng, D. Pearce

The paper determines the structure of mTORC2 and shows how substrate-specific interactions and conformational changes regulate its activity.

bioRxiv · Feb 3, 2022 · PreprintBiochemistry

Development and Application of a High-Content Virion Display Human GPCR Array

G.-D. Syu, S.-C. Wang, G. Ma, S. Liu, D. Pearce, A. Prakash, B. Henson, L.-C. Weng, D. Ghosh, P. Ramos, D. Eichinger, I. Pino, X. Dong, J. Xiao, S. Wang, , H. Zhu

The paper develops a high-content Virion Display (VirD) array of human GPCRs to profile their biochemical activities and identifies potential drug targets.

bioRxiv · Jul 26, 2018Pharmacology & Toxicology