T. Lan

CLAVATA signalling shapes barley inflorescence architecture by controlling activity and determinacy of shoot apical and rachilla meristems

This study identifies HvFCP1 and HvCLV1 as key regulators of barley inflorescence architecture by coordinating meristem activity and determinacy.

LEAFY and WAPO1 jointly regulate spikelet number per spike and floret development in wheat

This study identifies LEAFY and WAPO1 as regulators of spikelet number per spike and floret development in wheat through genetic and molecular interactions.

G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer

This study shows that G6PD is critical for redox balance and biosynthesis in LKB1-deficient KRAS-driven lung cancer, but not in KP tumors, and identifies potential therapeutic strategies.

Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans

This study identifies a regulatory axis involving acetylation and ubiquitination of Isw1 in Cryptococcus neoformans that controls multidrug resistance.

An updated nomenclature for plant ribosomal protein genes

The paper proposes updated nomenclature for plant ribosomal protein genes to improve adoption in plant biology, extending previous systems to include organellar ribosomes and additional species.

PPAR-γ activation promotes xenogenic bioroot regeneration by attenuating the xenograft induced-oxidative stress

This study shows that PPAR-γ activation with rosiglitazone reduces oxidative stress and promotes xenograft regeneration in a dental follicle cell model.

Comparative miRNA Transcriptomics of Mouse and Macaque Reveals MYOC is An Inhibitor for C. neoformans Invasion into Brain

Insights into bear evolution from a Pleistocene polar bear genome

This paper analyzes ancient and modern polar and brown bear genomes to study evolutionary history and gene flow, finding evidence of ancient introgression from brown bears into polar bears.

Slow TCA flux implies low ATP production in tumors

This study quantifies TCA flux in tumors and healthy tissues, finding suppressed ATP production in tumors despite increased glycolysis.

Screening of cell-virus, cell-cell, gene-gene interactions among kingdoms of life at single cell resolution

The paper screens cell-virus and cell-cell interactions across multiple species to identify potential hosts and co-evolution patterns of viruses including SARS-CoV-2.

Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics

The paper uses single-cell transcriptomics to profile viral receptor expression in masked palm civets, identifying potential tissue tropisms for 132 viruses.

Atypical DNA methylation, sRNA size distribution and female gametogenesis correlate with genome compaction in Utricularia gibba

The paper investigates DNA methylation and noncoding RNA in Utricularia gibba, finding reduced methylation and a defective DCL3 gene associated with genome compaction and developmental changes.

Single-cell screening of SARS-CoV-2 target cells in pets, livestock, poultry and wildlife

The paper screens SARS-CoV-2 target cells across 11 animal species using single-cell transcriptomes, finding higher proportions in cats and detecting them in multiple pig cell types.

Phenotype Spectrum reflects Synergies among the Cell Architecture over Stages of the Cell Cycle

The paper investigates the relationship between cell cycle phases and migratory behaviors in NIH 3T3 fibroblasts, showing synergies between cell cycle regulators and migration.

Altered Gene Regulatory Networks are Associated with the Transition from C3 to Crassulacean Acid Metabolism in Erycina (Oncidiinae: Orchidaceae)

This study compares gene regulatory networks between C3 and CAM species in Erycina to identify changes associated with the transition to CAM photosynthesis.