E. Dong

A Drug-Elicitable Alternative-Splicing Module (DreAM) for Tunable AAV Expression and Controlled Myocardial Regeneration

Vasoactive Intestinal Peptide Amphiphile Micelle Material Properties Influence Their Cell Association and Internalization

This study investigates how VIP amphiphile micelle properties affect macrophage association, finding that VPAC targeting enhances binding while shape and size influence long-term association.

Myocardial infarction creates a critical time window for AAV gene therapy

This paper shows that myocardial infarction creates a time window where AAV gene therapy is more effective in mice, improving gene expression and therapeutic outcomes when administered three days post-infarction.

Prenatal Stress Alters Transcription of NMDA-Type Glutamate Receptors in the Hippocampus.

This study shows prenatal stress increases NMDAR subunit transcription in the hippocampus of mice, correlating with reduced social behavior, and suggests a molecular pathway for stress-induced social deficits.

Non-cell autonomous cardiomyocyte regulation complicates gene supplementation therapy for LMNA cardiomyopathy

This study shows that gene supplementation for LMNA cardiomyopathy is ineffective when targeting cardiomyocytes alone, as non-cell autonomous effects dominate, suggesting alternative therapeutic targets.