F. C. Schroeder

Pheromone-dependent olfaction bidirectionally regulates muscle extracellular vesicles formation

The paper shows that pheromones both increase and decrease exopher production in C. elegans, regulated by sensory neurons and neuropeptides.

Mapping protein-metabolite interactions in E. coli by integrating chromatographic techniques and co-fractionation mass spectrometry.

The paper introduces PROMIS, a co-fractionation mass spectrometry technique integrated with chromatographic methods to map protein-metabolite interactions in E. coli, identifying 994 interactions and revealing novel functional insights.

ATP-release pannexin channels are gated by lysophospholipids

The paper identifies lysophospholipids as activators of pannexin channels, showing they trigger ATP and other metabolite release, and activate inflammasomes in human monocytes.

Natural genetic variation in the pheromone production of C. elegans

The paper identifies genetic factors influencing ascaroside pheromone variation in C. elegans using metabolomic and genomic analysis.

A D-2-Hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development

This study shows that in C. elegans, D-2HG is produced via the propionate shunt and that loss of dhgd-1 causes embryonic lethality by disrupting ketone body metabolism, which can be rescued by vitamin B12 or 3-hydroxybutyrate.

Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans

The paper introduces Metaboseek, a platform for untargeted metabolomics, and uses it to discover functions of a conserved fat metabolism pathway in C. elegans.

Modular metabolite assembly in C. elegans depends on carboxylesterases and formation of lysosome-related organelles

The paper identifies carboxylesterases and lysosome-related organelles as essential for modular metabolite assembly in C. elegans, including ascarosides and glucosides.

Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity

This study identifies isocyanides from Aspergillus fumigatus that bind copper, regulate its cellular levels, and exhibit copper-dependent antimicrobial activity.

Inversion of pheromone preference optimizes foraging in C. elegans

This study shows that C. elegans invert their pheromone preference based on when they leave a food patch, optimizing foraging efficiency through associative learning.

Selection and gene flow shape niche-associated copy-number variation of pheromone receptor genes

The paper shows that copy-number variation of pheromone receptor genes in C. elegans is shaped by selection and gene flow, contributing to differences in pheromone responses across habitats.

Attraction to pheromones in Caenorhabditis elegans can be reversed through associative learning

This study shows that Caenorhabditis elegans can reverse attraction to ascaroside pheromones through associative learning involving food deprivation.

Ethylene signaling regulates natural variation in the abundance of antifungal acetylated diferuloylsucroses and Fusarium graminearum resistance in maize seedling roots

The paper identifies two antifungal metabolites in maize roots and shows ethylene signaling regulates their ratio, affecting resistance to Fusarium graminearum.